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Investigating Pulmonary Immune Responses that Detect and Counteract Gram-negative Bacterial Infections

Brown, LukeCumming School of Medicine2025

… remains uncertain. Using genome-engineered P. aeruginosa strains, we compared EPS-producers versus non-producers and a virulent E. coli pneumonia model in mice to better understand detection. EPS-negative P. aeruginosa and virulent E. coli infection caused severe sickness mediated by TRPV1+ …

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