Global ETD Search
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Showing 1 to 4 of 4 for “"PstSCAB"”.
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Investigating the impact of phosphate acquisition and homeostasis on staphylococcus aureus pathogenesis
… three inorganic phosphate (Pi) transporters: PstSCAB, PitA, and NptA. Each transporter imports Pi optimally in distinct environments. Interestingly, although loss of PstSCAB results in decreased virulence of several well-studied pathogens, a ΔpstSCAB mutant of S. aureus was not attenuated. …
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Genetic analysis of conserved residues in PhoU of Escherichia coli
The Pho regulon is controlled by the PstSCAB transporter, PhoU, and the two-component proteins, PhoB and PhoR. PhoU is a negative regulator of the Pho regulon under phosphate-replete conditions. How PhoU functions is unknown. Many PhoU homologues are found widely throughout prokaryotic domains. …
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Investigating the role of phosphate homeostasis in Staphylococcus aureus virulence
… phosphate homeostasis by overexpression of the PstSCAB phosphate transporter or loss of function of the PhoPR phosphate sensing system reduces virulence. However, how phosphate homeostasis is controlled in S. aureus is yet to be discerned. S. aureus codes for three accessory regulators that may …
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Identification of novel regulators of the necrosis-inducing protein (Nip) and carbapenem antibiotic production in the phytopathogen Pectobacterium
… to pstA_2 and phoU which are part of the pstSCAB-phoU operon for phosphate uptake; expA which encodes the response regulator of the ExpS/ExpA two-component system and orf03204 - of unknown function. The orf03204 gene was part of a 10.5 kb likely transcript located within a novel 50.9 kb …