Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Pseudotyped virus"”.
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The study of highly pathogenic emerging zoonotic virus envelope proteins through pseudotyped virus generation
Emerging zoonotic viruses pose an increasing threat, causing outbreaks with high rates of morbidity and mortality and frequently significant economic implications. Often, there is a lack or shortfall of effective prophylaxis and diagnostic capabilities. Research towards their development, together …
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Factors affecting transduction efficiency of pseudotyped viral vectors incorporating alphaviral glycoproteins
… delivering this gene are known as vectors. Retroviruses are popularly used gene therapy/transfer vectors. However, retroviruses are limited in the range of cells they can enter and infect. The range of cells targeted by the viral vector can be either expanded or narrowed by replacing the envelope …
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Aptamers that bind SARS-CoV-2 spike protein for COVID-19 rapid diagnostics and therapeutics
The coronavirus disease 2019 (COVID-19) pandemic continues to severely impact healthcare and socioeconomic circumstances despite advances in rapid diagnostics and vaccines. One hurdle is the emergence of SARS-CoV-2 variants of concern, including the Omicron variant, which has enhanced infectivity …
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Formulation of Hyaluronidase Enzyme Sensitive Topical Nanomicrobicides for HIV Virus Transmission Prevention
… (TFV) can be used for the prevention of HIV virus vaginal transmission in women. To test this, a novel thiolated sulfhydryl (-SH) group modified HA (HA-SH) was synthesized to fabricate the TFV loaded HA-SH-NFs (mean diameter ~75 nm) using electrospinning method. Sulfhydryl (-SH) group …