Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 16 of 16 for “"Pseudotuberculosis"”.
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Iron-dependent regulation of gene expression in Corynebacterium pseudotuberculosis
This study set out to analyse C. pseudotuberculosis within an environment relevant to that which would be encountered within its natural host. The impact of the availability of iron within the growth environment of numerous bacteria has been widely reported, and an equivalent investigation was …
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Attenuation of Corynebacterium pseudotuberculosis by targeted mutagenesis of the phospholipase D gene.
… virulence determinant of Corynebacterium pseudotuberculosis, an animal pathogen which causes chronic, suppurative infections. In this study, PLD was purified from C. pseudotuberculosis biovar equi isolate 155 and the gene encoding PLD (pld) was cloned, pld from 155 and C. …
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Comparación de la capacidad hemolítica entre cepas de Corynebacterium pseudotuberculosis provenientes de ovinos, equinos y caprinos
Corynebacterium pseudotuberculosis es el microorganismo causante de la linfoadenitis caseosa en pequeños rumiantes, así como de la linfangitis ulcerativa y abscesos en equinos y bovinos, causando pérdidas económicas importantes ya que disminuye el rendimiento productivo del ganado. Uno de los …
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Estudos de imunobioinformática e imunoprofilático de uma proteína de fusão contra a infecção por Corynebacterium pseudotuberculosis em modelo murino
… was able to partially protect mice against C. pseudotuberculosis infection (57.14%), and can be considered as a potential new immunogen for the development of vaccines for CLA.
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Evolutionary dynamics of the Yersinia enterocolitica complex
… Yersinia pestis, enteropathogens Yersinia pseudotuberculosis and Yersinia enterocolitica as well as environmental species. The evolutionary history of Y. pestis has been well documented, but information on the evolutionary relationship between the other Yersiniae is less characterized. Y. …
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Uncovering novel pathogenicity-associated loci among Yersinia enterocolitica species by subtractive hybridization
… apathogenen Y. enterocolitica Stämmen noch in Y. pseudotuberculosis- und Y. pestis-Isolaten zu finden. Durch Inaktivierung des yts1E-Gens in Y. enterocolitica wurde eine Mutante hergestellt und hinsichtlich Mauspathogenität mit dem Mutterstamm verglichen. Bei oraler Infektion der Mäuse erwies sich …
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Investigation of the intracellular trafficking pathways of the dermonecrotic toxin family
… necrotizing factor Y (CNFY) from Yersinia pseudotuberculosis (Y. pseudotuberculosis), and the dermonecrotic toxin (DNT) from Bordetella species are related by sequence similarity and share similar intracellular GTPaseprotein targets. PMT, CNF1, CNF2, CNFY, and DNT are bacterial exotoxins …
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The determination of microbial quality and presence of pathogens and chemical contaminants in aquacultured rainbow trout (Oncorhynchus mykiss) fillets and whole fish from different aquaculture production systems
… Vibrio cholerae, Yersinia enterocolitica and Y. pseudotuberculosis) and general microbial quality of whole aquacultured rainbow trout (Oncorhynchus mykiss) were in compare differing aquacultural systems and growing seasons. Listeria levels and general microbial quality were determined on fillets …
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Novel anitbody-based assays for disease and food contaminant detection
… D (PLD) exotoxin of Corynebacterium pseudotuberculosis, the causative agent of caseous lymphadenitis (CLA), were investigated. A previously cloned recombinant form of PLD (Menzies et al., 1994) was expressed in E. coli, purified and subsequently used in an indirect ELISA and Biacore …
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Molekulare Analyse der Yersinien-Wirtszell Interaktion
… Für YpkA, dem zu YopO homologen Protein aus Y. pseudotuberculosis zeigte sich das gleiche Interaktionsverhalten. Durch Koimmunopräzipitation konnten die Ergebnisse der Yeast Two-Hybrid Untersuchung mit einer zweiten, unabhängigen Methode bestätigt werden. Aus dem Zellysat von mit Yersinien …
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New virulence mechanisms in Yersinia pestis, the plague (Black Death)-causing bacterium: A re-emerging and bioterror pathogen
Yersinia pestis evolved from Y. pseudotuberculosis to become the causative agent of bubonic and pneumonic plague. Y. pestis is also a category A select agent based on its potential use as a biological weapon. Currently, there is no vaccine licensed in the United States for use against Y. pestis so …
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A Structural Basis for Host Cytoskeletal Disruption and Virulence by Yersinia Protein Kinase A
… YpkA-induced cytoskeletal disruption. A Yersinia pseudotuberculosis mutant lacking the GDI activity of YpkA was significantly attenuated for virulence in a mouse infection assay as compared to wild type bacteria. We conclude that virulence in Yersinia depends strongly upon a novel mimicry of host …
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Dominant Suppression of Early Innate Immune Mechanisms by Yersinia pestis
… avirulent organisms. In contrast, <italic>Y. pseudotuberculosis</italic>, the relatively recent progenitor of <italic>Y. pestis</italic>, and <italic>K. pneumoniae</italic>, another highly virulent lung pathogen, show no similar trans-complementation effect, which is unprecedented among other …
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Studies on the mode of action of dermonecrotic toxins: Effects on adipogenic signaling pathways and delivery of c-terminal cargo into the cytosol
… coli (CNF1, CNF2 and CNF3) and Yersinia pseudotuberculosis (CNFY), and the mitogenic toxin from Pasteurella multocida (PMT). These relatively large (100-160 kDa), single polypeptide protein toxins share some regions of homology with one another in their protein sequence, which may account …
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Própolis verde como agente terapêutico no tratamento pós-cirúrgico da linfadenite caseosa
The treatment of caseous lymphadenitis with antibiotics is not effective, requiring the surgical excision of the lesions. The 10% iodine solution is currently the choice for the post-surgical treatment but may present histotoxicity. Considering that green propolis has proven to have antibacterial …
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UV Disinfection between Concentric Cylinders
Outbreaks of food-born illness associated with the consumption of unpasteurized juice and apple cider have resulted in a rule published by the U.S. Food and Drug Administration (FDA) in order to improve the safety of juice products. The rule (21 CFR120) requires manufacturers of juice products to …