Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 10 of 10 for “"Pseudomonas aeruginosa biofilm"”.
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The effect of antibiotics on Pseudomonas aeruginosa biofilm production
… burden worldwide. A highly resistant species is Pseudomonas aeruginosa, a nosocomial pathogen that produces a biofilm that enhances its resistance. This project examined the possibility of using bacteriocin, an internal protective toxin produced by some species of bacteria, as a potential …
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The genetics and phenotypes of Pseudomonas aeruginosa biofilm dispersal populations
… is due to the persistent colonization of Pseudomonas aeruginosa in the lungs, resulting in chronic pulmonary exacerbations. The ability to colonize CF patients’ lungs and other environmental habitats has been attributed to the large genome size of P. aeruginosa, and its ability to form …
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Influence of Indole and Mixed Culture Growth on Pseudomonas Aeruginosa Biofilm Structure
… multitudes of aggregates within surface-attached biofilm communities. The discovery of this sessile lifestyle has had a resounding effect on the scientific community and the approach toward studying anti-microbial resistance (AMR). Past studies showed that quorum sensing (QS) mutants of …
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Exoproteomics of the Pseudomonas aeruginosa biofilm matrix reveals the role of a novel secretion system
Pseudomonas aeruginosa is a WHO priority pathogen responsible for more than half a million deaths per year, whose reservoir of antibiotic resistance genes is expanding at an alarming rate. Even in the case of infecting strains that are genetically sensitive to drugs administered in the clinic, …
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Investigating the Role of the Antimicrobial Peptide TTO-53 in the Disruption of Pseudomonas aeruginosa Biofilm
Pseudomonas aeruginosa infections are commonly acquired in hospital settings and are oftentimes severe and deadly. P. aeruginosa is known for its resistance to a wide range of antibiotics due to the low permeability of its outer membrane, possession of various efflux pumps and modifying enzymes, …
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Non-Invasive Eradication of Biofilm on Metal Implants Using Alternating Magnetic Fields (AMF) and Antibiotics
… conventional antibiotics due to the formation of biofilm on the implant surface. Our group is developing a non-invasive method to eliminate biofilm on metal implants using alternating magnetic fields (AMF), utilizing the physical principle of electromagnetic induction. The aims of this …
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The dynamics of surface detachment and quorum sensing in spatially controlled biofilm colonies of Pseudomonas aeruginosa
Biofilms represent a highly successful life strategy of bacteria in a very broad range of environments and often have negative implications for industrial and clinical applications, as their removal from surfaces and the prevention of biofouling in the first place represent formidable and to date …
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DEVELOPMENT OF NOVEL COPOLYOXETANES: ANTIMICROBIAL AGENTS
… Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa showed MIC decreasing with increasing C12 mole% reaching a minimum between C12-43 and C12-60. C12-43 had the lowest MIC for all strains. At 5× MIC (challenge:108 cfu/ml), C12 43 kills ≥ 99% of the tested strains within 1 hr. …
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Exploring chemical communication and chemical heterogeneity in biological systems with mass spectrometry imaging
… to map quorum sensing (QS) pathways in Pseudomonas aeruginosa and to observe how the initial arrangement and polymer surface interactions of P. aeruginosa biofilms alter their quinolone profile. Finally, we utilize microMS, an optically-guided mass spectrometry single cell profiling …
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Structural and Functional Studies of Sensor Kinase RetS from Pseudomonas aeruginosa and Peptidoglycan Hydrolase SleB from Bacillus anthracis
… I: Signaling Role of the Sensor Kinase RetS in Biofilm formation Regulation of Pseudomonas aeruginosa-<br />The opportunistic human pathogen Pseudomonas aeruginosa causes both acute and chronic infections in predisposed individuals. Acute infections require a functional Type Three Secretion …