Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"Pseudohypoxia"”.
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Investigating pseudohypoxia in renal cells deficient in fumarate hydratase.
… oxygen conditions. This phenomenon, known as 'pseudohypoxia', is considered an important driver of tumorigenesis. However, the role of HIF activation and pseudohypoxia in FH-deficient renal cells is unclear. This aim of this thesis was to delineate the role of hypoxia biology in the phenotypic …
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"Interrogating the genomic and metabolomic landscape of pseudohypoxic phaeochromocytoma and paraganglioma syndromes"
… PAS domain protein 1 (EPAS1 or HIF2A) is another pseudohypoxia-associated gene that is rarely identified in sporadic PPGLs and, in the postzygotic somatic mosaic state, leads to the development of Pacak-Zhuang syndrome, associated with a high metastatic rate[6]. There is a critical need to develop …