Global ETD Search
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Showing 1 to 4 of 4 for “"Protozoan Proteins"”.
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The Protein Composition of the Chlamydomonas Flagellar Membrane Is Dynamically Regulated by Cilium-Generated Signaling During Fertilization
The cellular and molecular mechanisms specifying the membrane protein composition of cilia and flagella at steady state and during cilium-generated signaling are poorly understood. Our laboratory uses the biflagellated green alga Chlamydomonas as a model system to study regulated movement of the …
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Acanthamoeba spp. Secrete a Mannose-Induced Protein that Correlates with Ability to Cause Acanthamoeba Keratitis
Acanthamoeba spp. are ubiquitously distributed in the environment. The trophozoite form can infect the cornea and cause sight-threatening corneal inflammation known as Acanthamoeba keratitis. The pathogenic cascade of Acanthamoeba keratitis begins when Acanthamoebae bind to mannose expressed on …
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The Role of Glutathione Synthetase in Trypanothione Biosynthesis in Trypanosoma brucei
… effect, levels of biosynthetic pathway proteins were assessed by western blot analysis. A three-fold increase was seen in γ-GCS levels as well as a decrease in AdoMetDC prozyme and ODC levels. Thus our studies have shown that not only is TbGS essential for parasite growth but have also …
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Essentiality and Regulation of Deoxyhypusination in Trypanosoma brucei
Human African trypanosomiasis is caused by protozoan parasite Trypanosoma brucei. T. brucei and other trypanosomatids require spermidine for the formation of trypanothione, a unique thiol-redox factor. In other eukaryotes, spermidine is essential for the (deoxy)hypusination of eukaryotic initiation …