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Showing 1 to 20 of 20 for “"Proton radiation"”.
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Effects of Proton Radiation and Pomegranates on Hippocampus and Behavior
Exposure to ionizing radiation may have deleterious effects on physical and mental health, with an increased risk of proton radiation for astronauts traveling outside Earth's atmosphere into lower earth orbit. In animal models, radiation has been shown to suppress neurogenesis in the subgranular …
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Effects of Proton Radiation on Behavior in a Mouse Model of Alzheimer’s Disease
… magnetosphere risk exposure to charged particle radiation that has been shown to cause neurological deficits in rodents via oxidative stress, neuroinflammation, altered neurogenesis, and synaptic changes. Since these responses are similar to those observed in age-related neurodegenerative …
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VIABILITY OF CERIUM OXIDE NANOPARTICLES AS A RADIOPROTECTOR AGAINST PROTON RADIATION FOR NON-MALIGNANT CELLS
Radiation therapy is a prevalent cancer treatment therapy. The goal is to kill all tumor cells while minimizing damage to healthy cells and new methods that can accomplish this goal are continually being investigated. Cerium Oxide (CeO₂) or ceria nanoparticles have recently shown to act as a …
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Design and testing of an electron cyclotron resonance heating ion source for use in high field compact superconducting cyclotrons
… the potential to improve the availability of proton radiation therapy. Proton radiation therapy is a precisely targeted treatment capable of providing an excellent non-invasive treatment option for tumors located deep within tissue. In order to model injection into high field it is necessary …
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Investigating the Effects of Particle Radiation Exposure on Lung Carcinogenesis
… both men and women. The overall increase in radiation risk for human cancer types has been substantiated by the epidemiological data obtained from atomic bomb survivors and uranium mine workers. The lung has a large surface area which makes it a prominent target for radiation exposure making …
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Effects of Spaceflight on Phagocytic Function and Immune-Neural Interaction
… ground based studies have shown that low-dose radiation can also significantly impact immune function. Finally, as most spacecrafts are ecologically and environmentally closed systems, astronauts may be at increased risk for exposure to aerosolized infectious agents. The hypothesis of this …
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Acute Effects of Whole-Body Proton Irradiation on the Immune System of the C57BL/6 Mouse
<p>The acute effects of proton whole-body irradiation (WBI) on leukocytes, lymphocytes, and hematological parameters in the spleen and blood of C57BI/6 mice were examined and compared to the effects of photon (gamma) WBI derived from a 60cobalt (60Co) source. Adult, female C57BL/6 mice were exposed …
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Survivin: Regulation by YY1 and Role in Pancreatic Cancer Combination Therapy
… cancer. Using combined gemcitabine and proton radiation therapy, we show that downregulation of survivin and its family member X-linked IAP may lead improved cell death following treatment, particularly when gemcitabine therapy is instituted prior to proton radiotherapy.</p>
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Proton Computed Tomography: Matrix Data Generation Through General Purpose Graphics Processing Unit Reconstruction
<p>Proton computed tomography (pCT) is an image modality that will improve treatment planning for patients receiving proton radiation therapy compared with the current techniques, which are based on X-ray CT. Images are reconstructed in pCT by solving a large and sparse system of linear equations. …
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Dual Energy Computed to mography For Proton Therapy Treatment Planning
<p>Proton radiation therapy is gaining popularity because of the unique characteristics of its dose distribution, e.g., high dose-gradient at the distal end of the percentage-depth-dose curve (known as the Bragg peak). The high dose-gradient offers the possibility of delivering high dose to the …
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Assessing The Potential Clinical Impact of Variable Biological Effectiveness In Proton Radiotherapy
<p>It has long been known that proton radiotherapy has an increased biological effectiveness compared to traditional x-ray radiotherapy. This arises from the clustered nature of DNA damage produced by the energy deposition of protons along their tracks in medium. This effect is currently quantified …
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Assessment and Analysis of Commercial Off the Shelf Devices for Space Applications
… orbit to deep-space missions. However, the harsh radiation environment in space exposes electronic systems to intense cosmic rays and solar radiation, which poses significant risks of damage and failure. Ensuring the reliability and efficiency of these systems is therefore a crucial priority. This …
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Atrx Inactivation and Idh1-R132H Drive Preferential Sensitivity to Proton Vs. X-Ray Radiotherapy In Glioma Stem Cells
… In contrast to traditional photon-based radiation therapy (XRT), proton radiation therapy (PRT) may induce more complex DNA damage and therefore might have the potential to eliminate GSCs. Although previous studies have individually linked IDH mutations, specifically IDH1<sup>R132H</sup>, …
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Experimental investigation of the characteristics of prompt gammas produced in tissue during proton therapy treatment
Protons entering matter have a finite range while photons have a gradual, exponential attenuation as they travel through material. Proton radiation therapy takes advantage of this difference, by aligning the cancerous tissue with the end of the proton range where it deposits the maximum amount of …
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Modelling the Exposure of Satellites in Medium Earth Orbit to Proton Belt Radiation
Geomagnetically trapped protons forming Earth's proton radiation belt pose a hazard to orbiting spacecraft. In particular, solar cells are prone to degradation caused by non-ionising collisions with protons in the energy range of several megaelectron volts, which can ultimately shorten the lifespan …
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Ultra-thin GaAs Photovoltaics for Space Applications
… (<100 nm) have shown an intrinsic tolerance to radiation-induced damage which makes them a potentially advantageous power source for spacecraft which need to withstand harsh environments outside Earth’s atmosphere. In the ultra-thin regime, high transmission losses can be mitigated by …
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Evaluation of the performance of coherent optical communications commercial DSP ASICs in low earth orbit radiation environments
… must be evaluated with consideration of the radiation effects from the space environment. This work investigates the performance of the Inphi CL2001OA1 optical coherent DSP ASIC in a low earth orbit (LEO) radiation environment and assesses whether this ASIC could be a viable option for a …
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Study of Radiation Effects on FPGA and GPU based Neural Networks Accelerator Designs
… they are used in environments affected by radiation such as space exploration, medical devices, etc. Therefore, the reliability of IC devices in radiation-hazard environments has become an important issue. Energetic particles, such as protons, neutrons, and heavy ions, can penetrate the …
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Exploring poly (2, 5) benzimidazole enhanced with carbon nanotubes for space applications
… explores using polymeric materials for space radiation shielding in low-earth orbit. Shielding against radiation is essential on any space mission. Low atomic number materials, such as hydrogen, have shown to be effective in shielding ionising radiation. However, compared to metallic alloys, …
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Effects of Proton Irradiation on the Mechanical and Physical Properties of Carbon Nanotube Based Composites
In this study, the effects of proton irradiation on carbon nanotube (CNT)-epoxy composites are investigated for potential applications in radiation shielding for spacecraft. CNT-epoxy composites were prepared using multiwall and single wall CNTs and exposed to proton beams of energies ranging from …