Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 15 of 15 for “"Proton Relaxation"”.
-
Rotational Dynamics and Proton Relaxation of MRI Paramagnetic Contrast Agents
… play an important role in determining the relaxation characteristics of paramagnetic contrast agents (PCA's) used in magnetic resonance imaging. In this work, a methodology employing continuous wave electron paramagnetic resonance spectroscopy has been developed and established to probe the …
-
Proton relaxation studies of the interaction of small molecules with cytochrome P450
The effect of ferric cytochrome P450 on the proton relaxation cam times of a variety of small molecules has been studied. In some cases, Fe-proton distances in the small molecule-protein complex are determined. For water protons the following results are obtained: The substrate (camphor) complex of …
-
Effect of Nitroxides and Molecular Oxygen on Proton Relaxation Rates in Aqueous Systems and in Lipids
… is presented. The effect of these species on proton relaxation in both aqueous systems and in lipids is studied. The basic experimental approach for this study is the measurement of proton longitudinal relaxation rates (1/T$\sb1$) over a broad range of magnetic field strengths (corresponding …
-
EPR of powders, crystals, and clays of MRI contrast agents: zero field splitting and proton relaxation
… These agents increase the longitudinal proton relaxivity of protons in waters hydrogen-bound to the Gd III and indirectly affect nearby water protons. Gd DTPA (Magnevist) is the first Gd CA and has been widely used in imaging throughout the body. Gd DOTA (Dotarem) has been intensively …
-
Magnetic Resonance Behavior and Metal-Metal Interactions in Bimetallic Complexes of Pyridylmethylketazine
This study is on the NMR proton relaxation rates and metal-metal interactions of MM$\sp\prime$(PMK)$\sb{3}$(NO)$\sb3)\sb{4}\cdot{\rm xH\sb{2}O,}$ where M and M$\sp\prime$ are Co(II), Ni(II), Cu(II), and Zn(II), and PMK (pyridylmethylketazine) is the condensation of two molecules of 2-acetylpyridine …
-
Small Gadolinium Oxide Contrast Agents: A Novel Class of Multi-Modality Contrast and Therapeutic Agents
… presented. MR relaxometry and nuclear magnetic relaxation dispersion (NMRD) characterization of the water-proton relaxation properties of small particulate gadolinium oxide and gadolinium oxide albumin microspheres is provided in chapter 3. In chapter 4 the structure and magnetic properties of …
-
Magnetic resonance contrast-enhancing agents whose effects are altered by electric fields
… if they were accompanied by changes in water proton relaxation rates in the vicinity of the membrane, and thus become a powerful tool for studying neuronal activity and, ultimately, understanding how the brain functions. With that in mind, contrast-enhancing agents whose effects are changed by …
-
Crosslinking and Entanglement Effects in Polybutadiene
Proton relaxation measurements have been used to investigate the effects of crosslinking and entanglements on segmental motion in polybutadiene. The temperature dependence of T(,1), the spin-lattice relaxation time, T(,2), the spin-spin relaxation time, and T(,1(,(rho))), the spin-lattice …
-
Effect of 1B/1R Chromosomal Translocation on Dough Rheology of Soft Red Winter Wheat Flour
… selected 1B/1R and non-1B/1R dough samples. Proton relaxation time (T1-rho-[H]) - a ¹³C-NMR technique, indicated that water did not exert a significant influence on the molecular dynamics within the dough samples of Massey (non-1B/1R), VA54-211 (1B/1R) and VA52-22 (1B/1R). However, the …
-
Dynamic nuclear polarization of amorphous and crystalline small molecules
… but requires heavy deuteration to attenuate proton relaxation. Further application of DNP to nanocrystalline acetaminophen embedded in cellulose membrane as an undissolved suspension in organic solvent was less successful due to the fast methyl group motion within the acetaminophen molecule. …
-
Molecular Liquids and Polymers Investigated by Field Cycling 1H NMR Relaxometry: Impact of Rotational and Translational Dynamics on Relaxation
… (FC NMR) is applied to measure the spin-lattice relaxation time, T1, of proton spins in condensed matter not only at different temperatures but also at different Larmor frequencies, ω. The results are presented by means of six publications, from which the first four deal with viscous molecular …
-
Solid State NMR Relaxation Studies of Triosephosphate Isomerase
… of timescales from picoseconds to seconds. Spin relaxation measurements, including relaxation in the rotating frame (R1ρ), can be very sensitive to exchange processes in proteins, particularly on the millisecond-to-microsecond timescale. Using solid state NMR, few techniques exist that can …
-
Structure and dynamics of plant cell walls and membrane peptides from solid-state NMR
… measuring heteronuclear correlation spectra and proton relaxation times, we determined the localization of the Influenza M2 peptide in distinctly curved membrane domains. Using a rigid-solid heteronuclear correlation experiment, we were able to determine the depth of insertion of dynamically …
-
Applications of functional nucleic acids in imaging, sensing and drug delivery and investigations of DNAzyme-metal interactions
… analytes, which lead to analyte-specific water proton relaxation responses and contrast changes on an MRI image. The designs are general; the high selectivity of FNA was retained. Most FNA-based fluorescent sensors require covalent labeling of fluorophore/quencher to FNAs, which incurrs extra …
-
Dextran Magnetite as an NMR Contrast Agent
Made available in DSpace on 2017-07-06T18:42:13Z (GMT). No. of bitstreams: 3 Alameda_Jay_C_Jr_MS.pdf: 36399097 bytes, checksum: a08d9d029c3e486ed573a217b4bbf5e2 (MD5) Alameda_Jay_C_Jr_MS_ABS.pdf: 1261364 bytes, checksum: e54d7b39be48ea31cc1b6086ec21f499 (MD5) license.txt: 4813 bytes, checksum: …