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Showing 1 to 3 of 3 for “"Prothrombotic phenotype"”.

  1. Mechanisms of Hypoxia-Induced Neurovascular Remodeling in PlGF Knockout Mice

    … cause of the delayed angiogenic response and the prothrombotic phenotype of these mice. In vitro studies conducted to analyze mechanisms involved in the impaired angiogenic phenotype and enhanced astrocytic reactivity to hypoxia of PlGF-/- animals indicated that: i) PlGF-/- mouse brain endothelial …

    ottawa-retro Repository record for Mechanisms of Hypoxia-Induced Neurovascular Remodeling in PlGF Knockout Mice (opens in a new tab)

  2. Regulation of Syk activity in GPVI-mediated platelet activation

    … platelet functional responses and a prothrombotic phenotype. c-Cbl has been shown to be a negative regulator of GPVI signaling, possibly by regulating Syk phosphorylation. Thus, SHP-1, SHP-2 and TULA-2’s role in c-Cbl regulation of GPVI was also investigated. We show that TULA-2 is …

    temple Repository record for Regulation of Syk activity in GPVI-mediated platelet activation (opens in a new tab)