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Showing 1 to 14 of 14 for “"Prothrombin Time"”.
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Comparisons among genetically diverse lines of chickens for blood coagulation factors
Blood coagulation time was determined in five genetically diverse lines of chickens by the capillary tube method. Significant differences were found among lines for coagulation time suggesting genetic influences on this characteristic in chickens. Heritability of blood coagulation as estimated by …
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Studies on the pathology of arsanilic acid toxicity in calves
… of blood and urine were taken two or three times a week for analysis. After death, tissues were collected for histopathological examination. Following is a description of the most important findings: 1) Arsanilic acid, in this study, did not show the growth promoting properties for calves …
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Changes in the clotting viscoelasticity caused by cardiopulmonary bypass (CPB) surgery
… between 25 and 60 minutes to get results. This time frame is not useful for deciding what type of treatment to give to a patient. More importantly, the standard clotting tests is they cannot determine platelet function. The Thrombo-Visco Elastogram (TVE) is a new test that provides results in …
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Evaluation of hemostasis in hyperthyroid cats
… euthyroid cats > 8 years of age were studied. Prothrombin time (PT), activated partial thromboplastin time (aPTT), fibrinogen, antithrombin (AT), D-dimers, thrombin-antithrombin complexes (TAT), von Willebrand Factor antigen (vWF:Ag), and activity of factors VIII and IX were measured. An …
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In Vitro and in Vivo Pharmacodynamic Characterization of the Novel Plasma Kallikrein Inhibitor Pf-04886847
… reduced thrombus mass and prolonged both prothrombin time (PT) and activated partial thromboplastin time (aPTT). Overall, our results indicate that PF-04886847 is a novel, potent small molecule inhibitor of plasma kallikrein that would be useful for the treatment of kallikrein-mediated …
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Chrysophanol-8-O-glucoside Attenuates Platelet Activation Through Inhibiting MAPK and PKCε
… mice showed significantly prolonged bleeding times. Furthermore, CP-8-O-glc-glucoside was found to have a significant inhibitory effect on rat platelet aggregation ex vivo. In coagulation tests, CP-8-O-glcglucoside did not alter prothrombin time (PT), and it prolonged the activated partial …
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The Effects of Feeding Varying Concentrations of Vitamin a for One Year to Adult Dogs
… ME. Complete blood count, serum chemistry, prothrombin time, histological analysis of buccal mucosa, computed tomography of the tibia, and magnetic resonance imaging of the liver and tibia were performed. There were no effects of vitamin A on any parameters other than buccal mucosa (P ≥ …
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Characterization of OmpT: An outer membrane vesicle protease Escherichia coli that attenuates blood coagulation.
… generation and fibrin clot formation as part of prothrombinase. The fibrin clot immobolizes the pathogen and allows the immune system to target and destroy the bacterium. Our research has shown that pathogenic Escherichia coli O86a:K61 secretes the protease OmpT as part of outer membrane vesicles …
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The effects of hypothermia and acidosis on Haemostasis
… accurately reflect the clinical situation at the time. Blood was taken from 40 consenting healthy adults and 17 critically ill patients to examine the effects of hypothermia and acidosis upon “normal” clotting. The STart®4 coagulometer was used to assess the prothrombin time (PT) and the activated …
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Effects of algal docosahexaenoic acid in an extruded cat diet on nutrient digestibility, fecal characteristics and metabolites, and blood coagulation parameters and fatty acid profiles of plasma and red blood cell membranes
… oil or aDHA did not affect (P > 0.05) plasma prothrombin time (PT), partial thromboplastin time (PTT), or fibrinogen parameters. All cats remained healthy throughout the study. Serum triglyceride concentrations were within reference range, but were higher (P<0.05) for the CT diet when compared …
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Advantages of MesoRex shunt compared with distal splenorenal shunt for extrahepatic portal vein occlusion in children
… (2-18). Bloodwork analysis included albumin, prothrombin time (PT), partial thromboplastin time (PTT), International normalized ratio (INR), fibrinogen, total bilirubin, liver enzymes and platelets prior to and two-years-post shunt surgery. Rex vein patency was assessed preoperatively. …
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Effect of resection of localised pancreatic cancer on tissue-factor promoted pathways of thrombosis, cell invasion and angiogenesis
… Cellular TF activity and pro-coagulant activity (prothrombin time) of PC patients were measured using a coagulometer. Matrigel Invasion Chambers and Boyden chambers with collagen IV were used to measure cellular invasion. A two dimensional angiogenesis assay was used to evaluate tubule formation …
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Failure Mode Effects Analysis of Auto-verification in the Clinical Laboratory
… costs, improve quality and reduce turnaround times. Fortunately, advances in analytic and information system technologies allow for automation of some pre-analytical, analytic and post-analytic laboratory processes. This paper addresses the use of computer algorithms to increase the …