Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"Proteomics profiling"”.
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Origin and Correlates of Viral Rebound in SIV-Infected Rhesus Macaques Following Discontinuation of ART
… plasma viremia. Daily transcriptomic and proteomics profiling in peripheral blood following ATI identified early upregulation of pathways related to T cell signaling, cytokine responses, and metabolism prior to detectable plasma viremia, presumably reflecting initial viral replication in …
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Comprehensive Proteomic Analysis and Characterization of Human Bone Marrow Mesenchymal Stem/Stromal Derived Extracellular Vesicles
… composition of hBM-MSC-EVs using a quantitative proteomics analysis. hBMMSC-EVs were produced from 5 hBM-MSC donors characterized by Nanoparticle Tracking Analysis showed no differences in the hBM-MSC-EV concentration and size among the 5 donors (1.83 x 10¹⁰ ± 3.23 x 10⁹ /mL), with the mode …
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Characterization of the Hepatotoxicity of Rifampicin and Isoniazid
… human <em>FECH </em>is dependent on iron levels. Proteomics profiling analysis suggests that in the livers of <em>hPXR </em>mice (7) rifampicin may induce CYP450 changes associated with increased hydrazine reactivity with cellular proteins, (8) multiple [2Fe-2S]-containing proteins and (9) [Fe-S] …
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Characterisation of cardiac remodeling associated with pregnancy: providing insights to peripartum cardiomyopathy
… period postpartum than previously reported. Proteomics profiling confirmed the prolongation of cardiac hypertrophy in the postpartum and the involvement of the ubiquitin proteasome system (UPS) in the reverse remodeling of cardiac changes that occur during pregnancy. We also identified a set …
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Plasma Extracellular Vessicles, Exercise Resistnace and Cancer
… purify EVs from platelet poor plasma (PPP) for proteomics profiling via high-resolution mass spectrometry (SEC-MS). The SEC-MS method identified more proteins with higher precision compared to several conventional EV isolation approaches. We applied the SEC-MS method to identify the unique …
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Exploring Risk Factors of Alzheimer’s Disease Using Mouse Models
… networks. Integration of large-scale turnover profiling of over 10,000 proteins in 5xFAD and wild-type mice with multi-omic datasets demonstrated discordant mRNA/protein expression of amyloidome components, suggesting an interaction with β-amyloid (Aβ) may decrease protein degradation and …