Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"Proteins conformation"”.
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Membrane fragmentation by a 20-29 fragment of human islet amyloid polypeptide and rat amyloid polypeptide
<p>A key factor in the development of type II diabetes is the loss of insulin-producing pancreatic beta cells. The amyloidogenic human Islet Amyloid Polypeptide (hIAPP, also known as human amylin) is believed to play a crucial role in this biological process. Previous studies have shown that hIAPP …
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Interface Driven Dynamics at Nanoscales:Polymer thin films and Electrical Double Layer
… to biology, for example, folding and function of proteins, conformation change of DNA and ionic flow through cell membranes. EDL polarization is the ion accumulation or depletion in the EDL due to the potential of the metal surface. The conventional method of measuring the EDL polarization is by …
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Topology and geometry-based methods for quantifying the complexity of protein structures
… systems of filaments, such as those formed by proteins. In this dissertation we employ tools from knot theory in combination with available experimental data and molecular simulations to analyze the topological complexity of tau proteins. These proteins are involved in a class of …
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An assessment of the conformational profile of bombesin and its mammalian analogues using computational chemistry methods
Submitted in fulfilment of the requirements of the Degree of Doctor of Technology: Chemistry, Durban University of Technology, Durban, South Africa, 2011.
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Investigating protein folding by the de novo design of an α-helix oligomer
<p>Proteins are composed of a unique sequence of amino acids, whose order guides a protein to adopt its particular fold and perform a specific function. It has been shown that a protein's 3-dimensional structure is embedded within its primary sequence. The problem that remains elusive to …