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Showing 1 to 3 of 3 for “"Proteinase-activated receptor-2"”.

  1. The role of intracellular and extracellular cysteines in regulating human proteinase-activated receptor-2 (hPAR2) function

    … a member of the novel family of proteolytically-activated G-protein coupled receptors termed Proteinase-Activated Receptors (PAR), has recently been implicated in cardiovascular disease. Previous pharmacological studies have found that activation of hPAR2 by mast cell tryptase, (the major PAR2 …

    hull Repository record for The role of intracellular and extracellular cysteines in regulating human proteinase-activated receptor-2 (hPAR2) function (opens in a new tab)

  2. Stress-induced Alterations in Mast Cell Numbers and Proteinase-activated Receptor-2 Expression of the Colon:Role of Corticotrophin-releasing factor

    … cell and enterochromaffin (EC) cell numbers, and proteinase-activated receptor-2 (PAR2) expression in the rat colon. In addition, we aimed to investigate the involvement of corticotrophin-releasing factor in these stress-related alterations. Eighteen adult rats were divided into 3 experimental …

    ajou Repository record for Stress-induced Alterations in Mast Cell Numbers and Proteinase-activated Receptor-2 Expression of the Colon:Role of Corticotrophin-releasing factor (opens in a new tab)

  3. Neuroimmune Interactions of Enteric Neurons and Mast Cells: Friends or Foes?

    … Identified mast cell mediators involved were proteinases acting via proteinase activated receptor 2 (PAR2), prostaglandin D2 (PGD2) and interleukin 6 (IL-6). Immunocytochemical examination of rat small and large intestine, revealed frequent co-localization of corticotropin releasing peptide …

    lund Repository record for Neuroimmune Interactions of Enteric Neurons and Mast Cells: Friends or Foes? (opens in a new tab)