Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"Proteinaggregation"”.
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High-resolution characterization of structural changes involved in prion diseases and dialysis-related amyloidosis
Proteinaggregation ist die Ursache vieler Krankheiten, wie Diabetes Mellitus Typ 2, Parkinsonsche, Alzheimersche und Huntingtonsche Krankheit, spongiforme Encephalopathien, Stauungsinsuffizienz und Dialyse-assoziierte Amyloidose. All diesen Störungen liegt eine Proteinfehlfaltung zugrunde, die zur …
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Factors modifying the aggregation of atrophin-1 acting in cis and in trans
Ten polyQ (polyglutamine) diseases constitute a group of hereditary, neurodegenerative, lethal disorders, characterized by neuronal loss and motor and cognitive impairments. The only common molecular feature of polyQ disease-associated proteins is the homopolymeric polyglutamine repeat. The …
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Folding and aggregation of amyloid peptides
Aggregation of the Amyloid β (Aβ) peptide to amyloid fibrils is associated with the outbreak of Alzheimer’s disease. Early aggregation intermediates in form of soluble oligomers are of special interest as they are believed to be the major toxic components in the process. These oligomers are of …