Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 71 for “"Protein-lipid"”.
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Synthetic analogues of protein-lipid complexes
… stimuli. The association of PSMA with lipid 2-dilauryl-sn-glycero-3-phosphocholine (DLPC) produces polymer-lipid complex analogues to lipoprotein assemblies found in lung surfactant. These complexes represent a new bio-mimetic delivery vehicle with applications in the cosmetic and …
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Protein -Lipid Interactions in Soluble Nanoscale Lipid Bilayers
… the binding of steptavidin to biotinylated lipids and annexin to phosphoserine lipids in Nanodiscs."
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Atomic-level characterization of protein-lipid interactions using molecular dynamics simulations
Peripheral membrane proteins are structurally diverse proteins that are involved in fundamental cellular processes. Their activity of these proteins is frequently modulated through their interaction with cellular membranes, and as a result techniques to study the interfacial interaction between …
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Protein-lipid interactions in molecular pathways of Parkinson’s and Alzheimer’s diseases
… are characterised by the accumulation of proteinaceous pathogenic inclusions in the central nervous system. The key proteins involved in the pathogenesis of AD and PD are amyloid β 1–42 (Aβ42) and α-synuclein (αS), which cause the toxicity in AD and PD through aberrant interactions with …
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Advances in understanding protein-lipid interactions through biophysical and bioelectronic approaches
Intrinsically disordered proteins (IDPs) are those that to do not possess a well-defined three dimensional structure. As a result, they show great flexibility when it comes to adopting a suitable conformation based on the target of interest. However, due to the nature of the free energy landscape …
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Computational investigation of protein-lipid interactions and lipid modulation of membrane proteins
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2024-08-01
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Protein-lipid interactions in raft-exhibiting membranes probed by combined AFM and FCS
… entity, far from being an inert assembly of protein and lipids which separates cells from the surrounding environment. A multitude of biological processes, ranging from active transport of ions into and out of the cell, to the immune response, are regulated at the level of the plasma …
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Probing human disease through protein-ligand and protein-lipid interactions via molecular simulation
Submission original under an indefinite embargo labeled 'Open Access'. The submission was exported from vireo on 2025-03-28 without embargo terms
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Supramolecular Architectures in Molecular Medicine: Visualizing and Manipulating the Structure of Protein-Lipid Surfaces
… of linear dichroism on the distribution of protein orientation angle has revealed a constrained degenerate solution, which has impact on all attempts to describe protein orientation with this technique.
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Supramolecular Architectures in Molecular Medicine: Visualizing and Manipulating the Structure of Protein-Lipid Surfaces
… interest to science and technology. Lipoproteins, a complex of protein and lipid, serve as the primary transporter of cholesterol and other lipids throughout the body. There is a direct correlation between the presence of certain lipoprotein species and the incidence of coronary artery …
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Multiplex analysis of protein-lipid and protein-membrane protein interactions utilizing silicon photonic microring resonators
… for many biological functions. When soluble proteins interact with the cell surface, the crowded and complex environment can act as a signaling mechanism and influence blinding and activity. Parsing out the components of the membrane that influence binding is a time consuming process. There …
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Characterizing the Interaction of the ATP Binding Cassette Transporters (G subfamily) with the Intracellular Protein Lipid Environment
… highly conserved cellular transmembrane proteins that mediate the ATP-dependent translocation of substrates across membranes. Members of this superfamily, ABCA1 and ABCG1, are key components of the reverse cholesterol transport pathway. ABCG1 acts in concert with ABCA1 to maximize the …
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A Deuterium Nuclear Magnetic Resonance Study of Protein Dynamics and Protein-Lipid Interactions in Model and Biological Membranes (Nmr)
Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 1984.
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Structure, Assembly, and Maturation of High -Density Lipoproteins
High-density lipoproteins (HDL) are protein-lipid particles that are involved in the transport of cholesterol in the blood. They are of great importance in the treatment of coronary heart disease as low levels of HDLs are a known risk factor for the development of arteriosclerosis. Little is known …
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Structure, Assembly, and Maturation of High-Density Lipoproteins
High-density lipoproteins (HDL) are protein-lipid particles that are involved in the transport of cholesterol in the blood. They are of great importance in the treatment of coronary heart disease as low levels of HDLs are a known risk factor for the development of arteriosclerosis. Little is known …
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Lipid-protein interactions of immunoreceptor signaling subunit cytoplasmic domains
Protein-lipid interactions are emerging as key components of cellular processes such as protein and membrane trafficking and cell-cell signaling. Many proteins bind lipid reversibly, including cytoplasmic proteins involved in signal transduction, such as Ras and Src. Membrane binding is vital for …
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Structural and Functional Studies of the Human Saposin Proteins
The human saposins are four homologous activator proteins that are essential for the lysosomal degradation of sphingolipids (SLs) with small headgroups. They function in part to increase the solvent accessibility of these SLs to specific acid hydrolases by two proposed modes of action. In the …
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Structure, Function and Dynamics of G-Protein coupled Receptors
Understanding the function of membrane proteins is crucial to elucidate the molecular mechanisms by which transmembrane signaling based physiological processes,i. e., the interactions of extracellular ligands with membrane-bound receptors, are regulated. In this work, synthetic transmembrane …
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Redefining the specificity of phosphoinositide-binding by human PH domain-containing proteins
Lipids and proteins are two major components of cells, which are crucial for structural integrity and maintenance of cellular homeostasis by integrating various extracellular and intracellular cues. Lipids are involved in the regulation of cellular functions and can interact with proteins and …
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