Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"Protein sequence evolution"”.
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Language Models Predict Drug Resistance from Complex Sequence Variation
… neural language models trained on viral protein sequence evolution have shown promise in their ability to predict viral escape mutations, potentially enabling more intelligent therapeutic design [6]. Hie et al.’s work puts forth the key conceptual advance that viral escape from human …
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Alignment- and Alignment-refining Algorithms: Effects on Branch-length Estimation and Selection Pattern Analyses
… First, I investigated the effects of multiple-sequence alignment quality on branch-length estimation, which can influence downstream bioinformatic analyses such as estimating rates of evolution and divergence times. To quantify the accuracy of branch-length estimates, I devised a scale-free …