Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"Protein resistant"”.
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Evaluation of monolayer protected metal nanoparticle technology
… metal nanoparticles are capable of resisting protein adsorption, and if utilized as a coating could have broad application in a wide range of industries from consumer products to maritime shipping to medical instruments. The formation of proteic films can adversely affect the performance of …
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Engineering poly(ethylene glycol) nanogel coatings: Developments in achieving ultralow protein adsorption and applications as substrates for stem cell culture
… interface with its biological environment. Proteins irreversibly adsorb to these interfaces within seconds to minutes of exposure, altering their structural conformation, inducing cell adhesion, and activating various cellular responses. To this end, surface modification strategies have been …
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Biophysical regulation of cell motility by adhesion ligands and growth factors : effect of spatial presentation of the ligand
… receptors for the extracellular matrix (ECM) proteins initiate signaling cascades, some of which are in common with those initiated by growth factors. We have quantitatively investigated the potential synergy between growth factors and ECM ligands in governance of cell motility. In initial …
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A Point-of-Care Immunoassay for Ultra-Sensitive Detection of Ebolavirus
… lack of high-quality antibodies and nonspecific protein absorption (NSPA) on test substrates have historically hindered assay sensitivity and overall performance. While antibody development has witnessed a significant evolution over time, mostly driven by the interest in antibody-based drugs, …
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BIOFUNCTIONALIZATION ON HYDROGEN-TERMINATED SILICON(111) SURFACES
… (OEG) prepared using this apparatus remained resistant to model protein fibrinogen after 56 days in phosphate buffer saline (PBS). In order to incorporate new moieties to our platform, we optimized the design of trimethylgermanyl protected acetylenylated self-assembling molecule (SAM). …
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A computational approach for identification and development of novel inhibitors targeting viral polymerases
… the efficacy of antivirals against wide range of resistant mutations. Lack of effective therapies for these viral infections as most of the established treatments are not always effective or well tolerated, highlights an urgent need for further refinement and development of antiviral drugs. It is …