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Showing 1 to 1 of 1 for “"Protein quality control (PQC) system"”.
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THE INTERPLAY BETWEEN THE PROTEIN QUALITY CONTROL SYSTEM AND EXTRACELLULAR VESICLES IN THE DISPOSAL OF DISEASE-ASSOCIATED PROTEINS AND MIRNAS IN ALS AND FTD MODELS
… the insoluble forms of the TAR DNA-binding protein of 43 KDa (TDP-43) and its C-terminal fragments (CTFs) of 35 (TDP-35) and 25 KDa (TDP-25). The accumulation of TDP-43 into insoluble cytoplasmic aggregates is toxic for cells that prevent their formation and/or promote their degradation …