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Showing 1 to 9 of 9 for “"Protein microspheres"”.
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The Biomedical Applications of Protein Microspheres
Microspheres were produced containing a core of aqueous or organic liquids (i.e., microcapsules) or air (i.e., microbubbles). The microspheres were stabilized by a 60--100 nm protein shell (approximately 10 molecules). The small microsphere diameter (<5 microns) permitted the intravenous injection …
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Disulfide Cross -Linking in Protein Microspheres
Microspheres composed of either thiol-modified myoglobin or albumin have been extensively examined by a combination of techniques including SDS-PAGE, SEC, and MALDI mass spectrometry peptide mapping. Electrophoresis and chromatography confirm the presence of higher molecular weight protein units as …
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Production and Surface Modification of Protein Microspheres
… covalently linked to the surface of the albumin microspheres. A flow cytometry assay with KB cells, which express high levels of folate receptor, was unable to detect specific targeting of the microspheres under flow cytometry conditions.
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Methods to Tailor Protein Microspheres for Biomedical Applications
… modify the core, shell, and surface of the protein microspheres. In addition, I have shown that the size of these spheres can be reduced from the micron scale to the nano scale. These modifications have thus improved the versatility and the applicability of the microspheres to a variety of …
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Optical coherence tomography and targeted multi-modal protein microspheres for cancer imaging
Made available in DSpace on 2015-07-22T22:15:21Z (GMT). No. of bitstreams: 2 Nguyen_Freddy1.pdf: 44286913 bytes, checksum: 25adf2119dc8e21711fa930ef1d6461f (MD5) license.txt: 4062 bytes, checksum: 68620aadf6056c3614651a5a2c1c3fc5 (MD5) Previous issue date: 2015-03-18
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Controlled release of GLP-1 from affinity-based protein microspheres and quantitative analysis of the role of fiber length on phagocytosis and inflammatory response by macrophages
… 1 (GLP-1) using Src homology 3 (SH3) domain protein microparticles that bind GLP-1 through affinity-mediated interactions. GLP-1 modified with SH3-binding peptides of weak and strong affinities (GLP-1-SBPs) facilitate tunable release from SH3 microparticles. Release rates of GLP-1 from SH3 …
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Small Gadolinium Oxide Contrast Agents: A Novel Class of Multi-Modality Contrast and Therapeutic Agents
… gadolinium oxide and gadolinium oxide albumin microspheres for MR and CT imaging is presented. MR relaxometry and nuclear magnetic relaxation dispersion (NMRD) characterization of the water-proton relaxation properties of small particulate gadolinium oxide and gadolinium oxide albumin …
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Core -Shell Microspheres for Biomedical Applications
… delivery of drugs and imaging agents. Core-shell protein or polymer microspheres are biocompatible vesicles that have been used to meet the goal of transporting drugs or contrast agents to diseased tissues via the circulatory system. They consist of a hydrophobic core surrounded by a protein or …
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Development and characterization of biodegradable microspheres containing selected antimycobacterials.
… regimens. Biodegradable poly-a-hydroxy acid microspheres and microcapsules containing rifampicin (RIF) and isoniazid (INH) respectively have been prepared with the intention of providing high sustained site-specific concentrations to overcome some of the shortcomings of existing oral …