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Showing 1 to 3 of 3 for “"Protein domain families"”.
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Analysis of variation in protein domain families and interfaces
… availability of over 110,000 three-dimensional protein structures allows the structural context of many SNPs to be examined in atomic detail. Interfaces are essential sites for protein function and adaptation, and key in a majority of biological processes. A computational framework, ProIntVar, …
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Exploring the function and evolution of proteins using domain families
Proteins are frequently composed of multiple domains which fold independently. These are often evolutionarily distinct units which can be adapted and reused in other proteins. The classification of protein domains into evolutionary families facilitates the study of their evolution and function. In …
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Computational Discovery of Bacterial Fibrillar Adhesins and Adhesive Domains
… adhesins are filamentous bacterial surface proteins, which can play a key role in host-pathogen interactions. They have a characteristic protein architecture with repeating domains, called stalk domains, folding into a rod-like stalk structure. An adhesive domain is positioned at the tip of …