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Showing 1 to 3 of 3 for “"Protein crystal nucleation"”.
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On Protein Crystal Nucleation Precursors
Protein crystallization is central to our understanding of molecular structures in biology, vital to industrial processes in the pharmaceutical industry, and increasingly appreciated as a critical block in understanding numerous disease pathologies. Although the nucleation process is critical in …
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Particle assisted protein crystal nucleation as a protein purification platform for pharmaceutical manufacturing
Slow protein crystal nucleation is a major barrier to using crystallization as a separation and purification strategy in protein drug manufacturing. This work investigates the use of functionalized nanoparticles in solution to act as in situ templates for initiating crystal nucleation. We used …
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Coherent X -Ray Diffractive Imaging and Nucleation of Protein Crystals
The determination of the atomic structure of proteins is very important since much understanding of biological processes cannot be achieved without knowledge of the atomic structure. The preparation of high quality protein crystals suitable for structure determination often proves difficult and …