Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 11 of 11 for “"Protein clusters"”.
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Physicochemical Aspects of the Two-Step Mechanism of Nucleation in Protein Solutions
Protein-rich liquid clusters exist in solutions of numerous proteins. They play the role of nucleation precursors of ordered solids of both folded proteins and partially misfolded chains. Examples include protein crystals, sickle-cell hemoglobin polymers, and amyloid fibrils. The clusters hold the …
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Dual-Colour STED-microscopy on the Nanoscale
… in a variety of biological samples, including proteins of cell-junction and focal adhesion, or a neurofilamental protein from the human brain. Finally, the extension to a Dual-colour STED-microscope was achieved to provide nanoscale precise colocalization ability of individual protein clusters …
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Lokalisationsmikroskopie mit mehreren Farben und ihre Anwendung in biologischen Präparaten
… the relative distribution of a structural protein of the DNA (H2A) and a DNA remodeler protein (SNF2h) was examined. The experimental results were compared with random distributed signal positions within the same global structures. It could be shown that the real distributions are …
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Coordination among proteins, lipids and water in membrane fusion and fission probed by solid-state NMR
… membrane division. Viral membrane remodeling proteins catalyze membrane fusion and fission to bring about viral entry and exit from host cells – vital processes in the life cycle of enveloped viruses. The exact mechanism by which membrane remodeling proteins catalyze membrane fusion and …
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The roles of clustered membrane proteins in T-cell signaling
… a highly organized structure with some membrane proteins inhomogeneously distributed into clusters, which are often called protein islands or protein clusters. The roles of these clustered proteins remain to be established. For my thesis, to gain insights into the roles of protein islands in …
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Identification and Characterization of the Role of REEP5 in Sarco-Endoplasmic Reticulum Formation, Maintenance, and Function in Cardiac Muscle
… of all critical membrane and membrane-associated proteins in the heart by mapping several transcriptomic- and proteomic-based datasets against our mass spectrometry dataset of membrane-enriched protein clusters from human fetal and mouse neonatal cardiomyocytes. We identified 173 …
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CoryneRegNet : a reference database and analysis platform for corynebacterial gene regulatory networks
… interactions. Furthermore, it integrates protein clusters by means of heuristically solving the weighted graph cluster editing problem. In addition, it provides Web Service based access to up to date gene annotation data from GenDB. Conclusions: The release 4.0 of CoryneRegNet is a …
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Theoretical and lab based studies of fluorescence anisotropy toward the analysis of multiple homo-FRET pairs
Many biological functions, involve assembly of proteins. Protein clustering has an important role in signal transduction through the cell membrane. Model systems that simulate receptor aggregation can be used to monitor oligomerization. Techniques based on homo-FRET can reveal the aggregation state …
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Biomarker identification in HIV and non-HIV related lymphomas
… treated at GSH. Subsequent to this, potential protein biomarkers for DLBCL were determined using MALDI imaging mass spectrometry (IMS) and characterised using LCMS. The expression of one of the biomarkers, heat shock protein (Hsp) 70, was confirmed on a separate cohort of samples using …
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Dynamic localization of chemotaxis proteins in Bacillus subtilis
Understanding the subcellular localization of a protein or protein clusters is helpful to conceive the function of the proteins or the mechanism of the pathway involving these proteins. Bacteria, although small and single-celled, have been shown to have delicate subcellular locations for most of …
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The Role of Sulfatide in the Development and Maintenance of the Nodal and Paranodal Domains in the Peripheral Nervous System
… proper initial clustering of paranodal proteins and cluster maintenance of nodal proteins is impaired suggesting that paranodal domains are important for long-term node stability. In contrast to the CNS, a requirement for sulfatide in the initiation of myelination, and in initiation of …