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Showing 1 to 1 of 1 for “"Protein Multimerization"”.
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Thioredoxin-1 Inhibition Promotes MLKL Activation: Biochemical Insights Into a Suppressor of the Necroptotic Pathway
… strategy for identifying novel MLKL interacting proteins. Immunoprecipitation of NSA crosslinked MLKL complexes followed by mass spectrometric analysis revealed Thioredoxin-1, an essential cytosolic thiol oxidoreductase, to be a potential MLKL regulator. Based on its ability to reduce disulfide …