Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Protein Mimetics"”.
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Design and synthesis of protein mimetics via living polymerization of β-sheets-forming n-carboxyanhydride
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2024-08-01
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Interaction of amphiphilic nanoparticles with structurally perturbed lipid membranes
… applications such as drug delivery and membrane-protein mimetics. Perturbations such as area asymmetry and lateral tension affect these interactions by inducing various structural changes to the membranes. We use molecular dynamics simulations to demonstrate that the introduction of area …
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Design of Single-Chain Polymer Nanoparticles to Mimic Globular Proteins
While globular proteins exhibit an impressive range of precise functionalities, their sensitivity to environmental changes has motivated scientists to pursue two complementary strategies: (1) engineering and designing proteins directly or indirectly, and (2) exploring synthetic alternatives with …
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Investigating the molecular signatures of β1-adrenergic receptor activation
… receptor (β1AR) as a prototypical class A G-protein coupled receptor (GPCR). I have used a minimally thermostabilised turkey β1AR and expressed it functionally in insect cells using a baculovirus system. The work described here established the labelling, expression, purification and sample …