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Showing 1 to 20 of 33 for “"Protein Biosynthesis"”.
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Membrane protein biosynthesis at the endoplasmic reticulum
The biosynthesis of integral membrane proteins (IMPs) is an essential cellular process. IMPs comprise roughly 20-30% of the protein coding genes of all organisms, nearly all of which are inserted and assembled at the endoplasmic reticulum (ER). The defining structural feature of IMPs is one or more …
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Role of Chaperonin CCT in G-protein Biosynthesis
… and function to assist the folding of other proteins. All chaperonins consist of two stacked rings, which come together to form a central cavity where folding can take place. The eukaryotic cytosolic chaperonin containing TCP1 (CCT) is a member of the group II chaperonins, which are defined …
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Mechanism of the Transfer Reaction in Protein Biosynthesis
Made available in DSpace on 2014-12-09T17:35:20Z (GMT). No. of bitstreams: 1 6604156.pdf: 4046168 bytes, checksum: 3a87a159433cffdf5e245f97c8727e00 (MD5) Previous issue date: 1965
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Studies in Protein Biosynthesis. Role of Vitamin B12 and Rna
Made available in DSpace on 2014-12-05T17:47:39Z (GMT). No. of bitstreams: 1 6000216.pdf: 2459688 bytes, checksum: 5115bd08aed59ee78d9b931e150cffdb (MD5) Previous issue date: 1959
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The effect of thyroxine on protein biosynthesis and ribonucleic acid metabolism in the rat
… incorporation of radio labeled amino acids into protein of cell-free Liver systems from treated normal and hypothyroid rats. However, the in vitro addition of the hormone only had a stimulatory effect, though quite erratic in magnitude, on the normal system. This difference in response has not …
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The role of peptides as intermediates in protein metabolism
… that peptides may be intermediates in normal protein biosynthesis. This has also been inferred from certain disease states and other conditions under which protein biosynthesis is blocked at some point, e.g. cadmium, amino acid analogues or (in bacteria) antibiotics. The literature covering …
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BIOCHEMICAL ANALYSIS OF TWO DISTINCT METHIONYL-TRNA SYNTHETASES
… of amino acids to their cognate tRNAs for protein biosynthesis at the ribosome. The long term objective of this project is to investigate catalytic features of methionyl-tRNA synthetase (MetRS) from two different organisms. MetRS is proposed to use long-range communication between its …
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Η ΒΙΟΣΥΝΘΕΣΗ ΤΩΝ ΒΑΣΙΚΩΝ ΜΕΜΒΡΑΝΩΝ ΩΣ ΒΙΟΧΗΜΙΚΟΣ ΔΕΙΚΤΗΣ ΤΗΣ ΑΓΓΕΙΟΓΕΝΕΣΗΣ
… IS BASED ON THE RATE OF BASEMENT MEMBRANE (BM) BIOSYNTHESIS DURING EMBRYOGENESIS. MORPHOLOGICAL EVALUATION OF ANGIOGENESIS WAS ACHIEVED BY COUNTING VASCULAR DENSITY OF THE CAM FROM DAY 7 TO DAY 20 OF EGG INCUBATION.THE RATE OF BM BIOSYNTHESIS WAS MONITORED BY MEASURING THE INCORPORATION OF …
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The origin and evolution of the ribosome
… of the most fundamental biological processes, protein biosynthesis. The evolutionary history of the ribosome has intrigued biologists and it’s understanding has been a major and elusive challenge. In this dissertation, the evolution of the ribosome is studied using a novel method that directly …
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NMR studies of RNA binding domains of human lysyl aminoacyl tRNA synthetase
… tRNA synthetase which is primarily involved in protein biosynthesis as well as crucial processes ranging from proinflammatory response to signal transduction. One important, non-canonical function of hLysRS is to target lysyl tRNA isoacceptor 3, the HIV-1 reverse transcription primer molecule, …
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Discovery of Natural Product-based Antimycobacterial Agents Effective against Non-replicating Bacilli
… ((R)-20). UT-317 is a selective vitamin K2 biosynthesis (MenA) inhibitor that killed replicating and non-replicating Mtb at 2.31 μg/mL (MIC) and 0.85 μg/mL, respectively. A 50-membered library of capuramycin analogs was evaluated in their enzymatic inhibitory activities against translocase I …
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The cobalt cycle in the Tropical Pacific Ocean
… which catalyze critical steps in DNA and protein biosynthesis, respectively. Compared to other cyanobacteria, a streamlined metal physiology makes Prochlorococcus susceptible to competitive inhibition of cobalt uptake by low levels of zinc. Although phytoplankton in the Equatorial Pacific …
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Gene expression profile of ethanol-stressed yeast in the presence of acetaldehyde
… yeast. For example, many genes associated with protein biosynthesis were more highly expressed, as were pyruvate decarboxylase genes. Interestingly, however, there was no significant increase in the expression of trehalose synthesis genes or genes encoding HSPs; genes which, in previous studies, …
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Function of the PDLIM2 protein in oncogenic Wnt signalling pathways
… in oncogenesis. PDLIM2, a cytoskeletal PDZ protein, is an IGF-1 regulated gene that is highly expressed in cancer cell lines derived from metastatic tumours. Suppression of PDLIM2 inhibits polarized cell migration, reverses the Epithelial to Mesenchymal transition (EMT) phenotype, suppresses …
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The cobalt cycle in the tropical Pacific Ocean
… which catalyze critical steps in DNA and protein biosynthesis, respectively. Compared to other cyanobacteria, a streamlined metal physiology makes Prochlorococcus susceptible to competitive inhibition of cobalt uptake by low levels of zinc. Although phytoplankton in the Equatorial Pacific …
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Molecular, Genetic, and Agronomic Evaluation of Wp and Wp-M in Soybean
… to influence both anthocyanin production, and protein biosyntheses. Chimeric (purple and pink sectored) flowers were hypothesized to result from the genetic action of a wp-m transposable element. The objectives of this research were to (1) clone a 3'5' flavonoid hydroxylase enzyme from the …
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Membrane mechanism of progesterone actions on the rat brain
… Second, P's effects are insensitive to protein biosynthesis inhibitors. Finally, responses of P's actions on the CNS are more rapid than most documented genomic responses of steroids. There are several advantages of using the P-BSA complex instead of P itself to study the nongenomic …
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Isolation and characterisation of a LEA-like protein from yeast (Saccharomyces cerevisiae)
LEA proteins are plant proteins that are characteristically hydrophilic and soluble at elevated temperature. The consistent correlation between desiccation tolerance in orthodox seed tissue and an accumulation of LEA proteins suggests that these proteins play an important role in protecting cells …
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Age-related changes in renal function, membrane metabolism, transporter activity and abundance in hypokalemic Fischer 344 x Brown-Norway F1 rats
… (BBM) and basolateral membrane (BLM) protein and lipid metabolism, transporter activity and abundance were examined in non-obese male Fischer 344 x Brown-Norway Fl rats of 4 mo and 30 mo of age. These experiments were designed to examine whether age-associated changes occur in these …
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