Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 10 of 10 for “"Protein Biology"”.
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Characterization of self-assembling peptide nanofibers of KLD12 and RID 12
… areas, from tissue engineering to membrane protein biology. This work is to further study the characteristics of the peptides KLD12 and RID12 and to generate new ways to control the properties of them. Peptide structures in solution were studied with circular dichroism and dynamic light …
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A Systems Biology Approach to Study Type III and Type IV Bacterial Effector Properties
… between Type III and Type IV bacterial effector proteins and host signal transduction enzymes is a critical interface that, in many cases, determines the outcome of infectious disease. While many pathogenic strategies, such as evasion of phagolysosomal fusion, have been identified as necessary …
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Role Of Phosphoglucan Phosphatases In Regulating Starch Degradation In Plants
… are members of the dual- specificity protein phosphatase (DSP) family, which includes starch excess 4 (SEX4) and like-SEX4 1 (LSF1). SEX4 is required for proper glucan dephosphorylation; however, whether LSF1 participates in starch degradation is unknown. Moreover, how the activity of …
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Laying the Genetic and Molecular Foundation for the Study of Fusobacterium Nucleatum in Relation to Human Health and Disease
… functions to just a handful of Fusobacterium proteins (Fap2, FadA), and only two of those proteins have a well-defined role in the host-pathogen relationship. This dissertation contains work that lays the molecular and genetic foundation for future studies involving F. nucleatum by creating a …
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Characterising the conformational dynamics of β₁-adrenergic receptor activation and G protein coupling
The G protein-coupled receptor (GPCR) family of seven-transmembrane signalling proteins facilitates cellular responses to environmental stimuli. GPCRs are integral to numerous physiological signalling pathways and thus many therapeutics have been developed to modulate receptor activity. Stimulation …
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Elucidating Mechanisms of Biofluorescence and Bioluminescence in Marine Organisms
… research presented here will look at separate proteins to uncover their molecular interactions that lead to light generation. We combine transcriptomics, phylogenetics, and biochemical assays to unravel these mysteries. We have studied fluorescent fatty acid binding proteins to discover which …
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Computational modeling of peptide-mediated charge transport and membrane-associated phenomena
Proteins and membranes play a crucial role in fueling cellular activity and maintaining cellular homeostasis. Proteins act as energy conduits within cells by shuttling electrons through a series of reactions to fuel the synthesis of adenosine triphosphate (ATP). In mitochondria, membranes provide …
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Engineering Synthetic Biomolecular Condensates with Rationally-Designed Modular Repeat Proteins
… through phase separation of biomolecules such as proteins and nucleic acids, BCs exhibit remarkable structural and functional plasticity, resulting in their versatile material states and functional diversity across various cell types. Advances in microscopic techniques and computational …
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Yeast Dynamin Functions with Clathrin at the Golgi
Vps1 (vacuole protein sorting) is a GTPase protein and a yeast ortholog to the mammalian dynamin-like protein (Dlp1). Vps1 acts cooperatively with many proteins at diverse cellular locations for endocytosis, protein sorting, and membrane fusion and fission. Classical dynamin family proteins work in …