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Mechanistic Investigation into the Regulation of Amyloid Motifs in Tau Aggregation and Disease

Chen, Dailu2022

Amyloid formation of tau protein is a unifying theme in a multitude of neurodegenerative diseases, collectively called tauopathies. Missense mutations in the tau gene (MAPT) correlate with aggregation propensity and cause dominantly inherited tauopathies, but the molecular mechanism of how they …

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