Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 39 for “"Protein 5"”.
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Engineering Mussel Foot Protein 5 (MFP5) for Enhanced Adhesive Performance in Tendon and Bone Repair
… study explores the development of Mussel Foot Protein 5 (MFP5) bioadhesives to improve tendon-to-tendon and tendon-to-bone adhesive outcomes. MFP5, known for its underwater adhesive properties, was synthesized using recombinant techniques and optimized through coacervation and cross-linking. …
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Towards understanding of plasmodesmal association and regulation using Plasmodesmata-Located Protein 5 as a model
… molecules in plants. Despite a growing number of proteins are identified to associate with PD and affect PD permeability, not much is known about how they are targeted to PD and regulate PD function. Arabidopsis Plasmodesmata-Located Protein 5 (PDLP5), a receptor-like type I transmembrane protein …
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Progesterone Regulation of Insulin like-Growth Factor : Binding Protein-5 Gene Transcription in Human Osteoblasts
<p>Insulin-like growth factor binding protein-5 (IGFBP-5) is produced by osteoblasts and potentiates IGF mitogenic actions in osteoblast cultures. Progesterone (PG) increases osteoblast proliferation and increases osteoblast IGFBP-5 expression. Mechanisms underlying PG induction of IGFI3P-5 …
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The PHD finger protein 5 is a part of the spliceosome and acts as a DNA-binding protein
Vier Proteine: U2AF35, SRp40, mDomino und Ddx1 wurden durch Screening Yeast-two hybride-Bibliothek als Partner des PHF 5a-Protein gefunden. Proteininteraktionen wurden in-vitro und in-vivo bestätigt. Die für Bindungen verantwortlichen Domäne wurden als RS Domäne (reich an Arginin-Serin) …
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The Impact of Calcium Binding Protein 5 (CaBP5) on Synaptic Vesicle Dynamics in Rod Bipolar Cells in the Retina
<p>Calcium binding protein 5 (CaBP5) is a retina-specific protein, specifically expressed in rod bipolar cells and in type 3 OFF and type 5 ON cone bipolar cells. Rod bipolar cells (RBCs) are essential for rod pathway signaling in the vertebrate retina, and they form ribbon style synapses that …
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Thermodynamic and Structural Characterization of the Interaction between Wd40 Repeat Containing Protein 5 (Wdr5) and Human Set1 Family Methyltransferases
… structures of these peptidomimetics reveal novel protein structural features that contribute to increased affinity. We also present preliminary evidence suggesting that the MLL3 Win motif based peptide that has a cell penetrating sequence is readily taken up by mammalian cells. This MLL3 Win …
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An investigation of insulin-like growth factor binding protein-5 (IGFBP-5) as a biomarker for the detection of early liver disease
… proposed was insulin-like growth factor-binding protein-5 (IGFBP-5). IGFBP-5 is known to be involved in the wound healing response in epithelial tissues, and its expression is switched on in fibrosis of the lung. IGFBP-5 induces epithelial cell senescence, an important component in the failure to …
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WDR5 Network Analysis Using Ensemble Approaches
<p>Understanding the properties of protein-protein interactions (PPIs) is necessary to deconvolute the processes inside living organisms. As such, research in this regard has significant implications for gaining insight into cancers and other diseases. Once understood, drugs can be designed to …
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Strukturní a funkční charakterizace inhibice flavivirové methyltransferázy.
… RNA, po jejíž translaci vzniká dlouhý virový polyprotein štěpen hostitelskými a virovými proteasami na strukturální a nestrukturální proteiny. Nestrukturální protein 5 (NS5) je tvořen C-koncovou doménou s funkcí RNA- dependentní RNA-polymerasy (RdRp) a N-koncovou doménou s funkcí methyltransferasy …
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Regulation of HIF-1α during Hypoxia by DAP5-Induced Translation of PHD2
<p>Death associated protein 5 (DAP5) is an atypical isoform of the translation initiation scaffold eukaryotic initiation factors 4GI and II (eIF4GI/II), which recruit mRNAs to ribosomes in mammals. Unlike eIF4GI/II, DAP5 binds eIF2β, a subunit of the eIF2 complex that delivers methionyl-tRNA to …
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Molecular regulation of neuronal apoptosis in PC12 cells.
… and IGFBP2 (Insulin-like growth factor binding protein 2) were both upregulated by 3 and 4 fold respectively. Cathepsin B (RSG-2) and RSG-3 (embigin) exhibited marginal changes in expression, only about 1.2 fold, over the 24 hour time course. Finally, IGFBP5 (Insulin-like growth factor binding …
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The G protein-coupled receptor GPR30 signalosome - A novel G protein-independent mechanism regulating cAMP signaling and receptor trafficking
The large protein family called G Protein-coupled receptors (GPCRs) has co-evolved with life throughout evolution; from single cell organisms all the way to complex beings such as us humans. The fact that GPCRs are involved in essentially every physiological event, and that ~50% of drugs on the …
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Regulation of IGFBP-5 and Osteoblast Functions by Nuclear Factor I
… found that GCs inhibit expression of IGF binding protein-5 (IGFBP5) which binds IGFs and stimulates osteoblast activity by IGF dependent and independent mechanisms. GC-induced inhibition of IGFPB5 promoter activity was mediated by a composite response element that has binding sites for …
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Η έκφραση του γονιδίου CKAP5 σε κοκκώδη κύτταρα γυναικών που υποβάλλονται σε πρωτόκολλα εξωσωματικής
… Το γονίδιο CKAP5 (Cytoskeleton Associated Protein 5) κωδικοποιεί μια πρωτεΐνη, η οποία κατέχει καθοριστικό ρόλο στην ρύθμιση της δυναμικής των μικροσωληνίσκων και στην σωστή οργάνωση της μιτωτικής ατράκτου. Διαταραχές στην έκφρασή του, έχουν συσχετιστεί με προβλήματα στον κυτταρικό …
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Local regulation of increased milk yield due to early lactation increased milking frequency
… IMF significantly increased milk, fat, and protein yields in the right udder halves by 2.27 kg/d, 73.5 g/d, and 68 g/d respectively through the first 210 DIM (P < 0.001). At d 21, the right udder halves had a significant increase in activated signal transducer and activator of transcription …
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Fas-associated factor 1 is involved in neurofibrillary tangle-mediated cell death of basal forebrain cholinergic neurons in P301L transgenic mice
… disease 3 D. Normal functions of tau protein 4 E. Structure and Posttranslational Modifications of the Tau Protein 5 F. Distribution of tau phosphorylation sites and NFT formation in AD brains 7 G. Monoclonal antibody AT8 recognizes tau phosphorylation 11 H. Cholinergic dysfunction in …
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Paneth Cell-Dependent Intestinal Homeostasis During T. Gondii Infection
The intestinal epithelial barrier faces the arduous task of constantly monitoring and controlling the diverse bacteria which colonize the gut. Key for this balance are the Paneth cells, highly specialized secretory epithelial cells in the intestinal crypts which secrete anti-microbial peptides to …
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Cellular mechanisms of environmental enrichment: Novel discovery-based strategies for target identification for neuropsychiatric disorders
… transcriptomic/proteomic analysis of mRNA and protein regulated by enrichment and cocaine. This strategy identifies AKT signaling as a promising pathway; therefore, we knocked down the downstream target of AKT, glycogen synthase kinase 3 (GSK3) beta, with a novel adeno-associated viral (AAV) …
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