Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 6 of 6 for “"Prostatic acid phosphatase"”.
-
Analysis of N-Linked Oligosaccharides of Prostate-Specific Antigen and Prostatic Acid Phosphatase in Prostatic Fluids
… non-cancerous conditions as well, such as benign prostatic hyperplasia (BPH). Due to this overlap, many unnecessary biopsies and radical prostatectomies occur, leading to patient distress. Despite recent advances to clinical assays which consider other clinical parameters, there is still a great …
-
Development of prostrate cancer vaccine using PAP as target antigen
… still remain limited and rarely curative. The prostatic acid phosphatase (PAP) is prostate specific protein over-expressed in more than 90% of prostate tumours. Although an FDA-approved vaccine for the treatment of advanced prostate disease, PROVENGE® (sipuleucel-T), has been shown to prolong …
-
Characterizing glucocorticoid receptor in metastatic castration resistant prostate cancer
… Prostate Specific Membrane Antigen (PSMA) and Prostatic Acid Phosphatase (PAP) were inhibited by a novel GR inhibitor. Thus, this GR inhibitor could be used in combination with enzalutamide and create a more potent AR signaling blockade. Prostate cancer is a very problematic disease in men and …
-
Purification and Characterization of the Prostate Cancer-Associated Antigen: 7E11-C5
… cell line, LNCaP, and tissue extracts of benign prostatic hyperplasia (BPH) and prostate carcinomas, but was not identified in any of the non-prostate tissue extracts tested. Antibodies of the three major prostate-associated antigens (prostatic acid phosphatase (PAP), prostate specific antigen …
-
Novel urinary and serological markers of prostate cancer using proteomics techniques: an important tool for early cancer diagnosis and treatment monitoring
… We compared the urinary proteomes of PCa, Benign Prostatic Hyperplasia (BPH), disease controls comprising patients with other uropathies (DC) and normal healthy controls (NC) both by pooling and individual discovery shotgun proteomic assessment on a nano-Liquid chromatography (nLC) coupled Hybrid …
-
The identification of prostate cancer associated tumour antigens and biomarkers
… albumin and existing PCa biomarkers - human prostatic acid phosphatase & zinc-alpha-2 glycoprotein. Differential autoantibody responses were also identified to various TAAs in the PC-3 and DU-145 PCa cell lines using PCa and healthy sera. The presence of a differential TAA and autoantibody …