Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"Prostatic Neoplasms - Microbiology; Antigens, Tumor-Associated;"”.
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The Potential Role of LEDGF/p75 in Prostate Cancer
… being exploited for the identification of tumor associated antigens (TAA) and the design of TAA arrays. Such arrays would facilitate autoantibody profiling and potentially aid in the serological diagnosis and prognosis of tumors. The goal of this study was to identify and characterize …
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Biochemical and Functional characterization of the LEDGF/p75-MeCP2 Interaction in Tumor Cells
… protein is highly expressed in prostate tumors and other tumor types and promotes resistance to chemotherapy in cancer cells. LEDGF/p75 is also involved in acquired immunodeficiency syndrome (AIDS) since it interacts with HIV-1 integrase to facilitate the integration and replication of …
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Contribution of LEDGF/p75 to Prostate Cancer Chemoresistance
… the mechanisms by which this drug kills prostate tumor cells, and the genes that promote this resistance. We investigated the mechanism underlying DTX-induced death and observed that it involved the concomitant activation of caspase and lysosomal pathways. We also investigated the role of the …