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Showing 1 to 20 of 39 for “"Prostate specific antigen (PSA)"”.

  1. Design, Synthesis, and Screening of Novel Phosphatidylinositol 3-Kinase (PI3K) Inhibitors Activated by Prostate Specific Antigen (PSA): Prodrug Treatment for Androgen-Independent Prostate Cancer

    Nelson, Ronald AlvinWake Forest University2017

    … drugs are potent, but often lack the cellular specificity needed to lower toxicity effects. Here we show the design and synthesis of two types of novel PSA-activated PI3K inhibitors for the treatment of androgen-independent prostate cancer. Both literature and predictive molecular modeling …

    wfu Repository record

  2. ΔΙΕΡΕΥΝΗΣΗ ΤΟΥ ΡΟΛΟΥ ΤΟΥ ΕΙΔΙΚΟΥ ΠΡΟΣΤΑΤΙΚΟΥ ΑΝΤΙΓΟΝΟΥ (PSA) ΣΤΗΝ ΠΑΘΟΛΟΓΙΑ ΤΟΥ ΠΡΟΣΤΑΤΗ

    Περιμένης, ΠέτροςUniversity of Patras1988

    WE MEASURED SERUM PROSTATE SPECIFIC ANTIGEN (PSA) FROM 135 MEN (55 PROSTATE CANCER, 39 BENIGN PROSTATE HYPERTROPHY, 9 PROSTATITIS, 32 NORMAL). PSA IS A SPECIFIC-CELL TYPE ANTIGEN OF PROSTATE AND IS MORE SENSITIVE MARKER THAN PROSTATE ACID PHOSPHATASE (PAP)-71% TO 27,3%. PSA CAN NOT SOLVE THE …

    greece Repository record

  3. Integrative Bioinformatics Approaches to Elucidating Prostate Cancer Cell Heterogeneity, Plasticity, and Treatment Response

    Chao, Hsueh-Ping, <p>https://orcid.org/0000-0001-9404-4300</p>2019

    <p>Prostate cancer (PCa) is the most common non-cutaneous tumor in American men, and the second leading cause of cancer-related deaths. PCa-related deaths can be attributed to heterogeneous tumors containing metastatic and therapy-resistant cancer cells. Cancer stem cells (CSC) are an important …

    uthsc Repository record

  4. Ankstyvosios diagnostikos programos poveikio sergamumui priešinės liaukos vėžiu Lietuvoje vertinimas /

    Adomaitis, Robertas,Institutional Repository of Vilnius University2012

    Prostate cancer is most common and second deadliest tumour diagnosed in Lithuanian men. Prostate specific antigen (PSA) test in early detection of prostate cancer could result in decreased morbidity and mortality. Radical treatment of low-risk prostate emerged as an inevitable satellite of early …

    vilnius Repository record

  5. An MRI compatible manipulator for prostate cancer detection and treatment

    DeVita, Lauren MMassachusetts Institute of Technology2007

    Prostate cancer is the most frequently diagnosed cancer in men and the second most common cause of cancer related death in men. Prostate specific antigen (PSA) blood tests and digital rectal exams (DRE) are preliminary tests that can suggest the presence of prostate cancer. Following these tests, a …

    mit Repository record

  6. Nanomaterials for the detection of cancer-associated biomarkers

    Mu, Chunyao JennyMassachusetts Institute of Technology2010

    Prostate cancer persists as a major public health issue in the United States and remains the second leading cause of cancer death in men. Early detection and disease monitoring in prostate cancer can significantly improve a patient's prognosis. The advent of prostate-specific antigen (PSA) …

    mit Repository record

  7. Prostate Specific Antigen Screening in Texas Medicare Population: The Role of Patient Characteristics

    Edge, DarsheThe University of Texas Medical Branch at Galveston2016

    … study were to 1) determine the prevalence of prostate specific antigen (PSA) testing in the Texas Medicare population and 2) assess which patient characteristics are associated with receipt of PSA screening. The 100% Texas Medicare claims data and 2009 population estimates from the Dartmouth …

    utmb Repository record

  8. Antibody-based biosensor assays for the detection of zilpaterol and markers for prostate cancer

    Dillon, MaryDublin City University2008

    … and the application of antibodies against prostate-specific antigen (PSA), a cancer marker. Polyclonal antibodies were used in the development of immunoassays in a competitive ELISA format and on the Biacore (a surface plasmon resonance-based optical biosensor capable of monitoring …

    dcu Repository record

  9. Investigation of the anti-cancer effects of rosemary (Rosmarinus Officinalis L.) extract in human breast and prostate cancer cells

    Jaglanian, AlinaBrock University2019

    Breast and prostate cancer are the most frequently diagnosed cancers in women and men respetively, in North America. Triple-negative breast cancer (TNBC) cells do not express estrogen receptor, progesterone receptor, and human epidermal growth factor receptor-2 (HER-2). TNBC accounts for 15% of all …

    brock Repository record

  10. Fluorescence resonance energy transfer-based biosensors for monitoring prostate specific antigen

    Mu, Chunyao JennyMassachusetts Institute of Technology2005

    Prostate cancer has become the most commonly diagnosed cancer in men in the United States. Clinical diagnostic procedures currently include prostate-specific antigen (PSA) screening, digital rectal exam, and prostatic needle biopsy. However, these methods lack the sensitivity to detect small …

    mit Repository record

  11. Characterizing glucocorticoid receptor in metastatic castration resistant prostate cancer

    Kahn, Matthew Adam2020

    … in the context of enzalutamide resistant prostate cancer cells. Enzalutamide is a drug that functions to dampen androgen receptor (AR) signaling, thus inhibiting cancer dependency on the receptor protein. Although the application of the drug reduces AR signaling in these cancer cells, an …

    bu Repository record

  12. Prostate-specific Antigen Nadir and Time to Prostate-specific Antigen Nadir Following Maximal Androgen Blockade Independently Predict the Prognosis in Patients with Metastatic Prostate Cancer

    홍, 석영2013

    PURPOSE: To evaluate the influence of prostate-specific antigen (PSA) kinetics following maximal androgen blockade (MAB) on the disease progression and cancer-specific survival in patients with metastatic, hormone sensitive prostate cancer. MATERIALS AND METHODS: One hundred thirty-one patients …

    ajou Repository record

  13. Risk Factors for Acute Prostatitis after Transrectal Biopsy of the Prostate

    김, 상진2011

    … with acute prostatitis after transrectal prostate biopsy. MATERIALS AND METHODS: We retrospectively reviewed the medical records of 923 transrectal ultrasound-guided needle biopsy of the prostate on 878 patients performed in our institution from June 2004 to May 2009. The indications for …

    ajou Repository record

  14. Differences in Lower Urinary Tract Symptoms between Sympathetic Hyperactive and Hypoactive men

    오, 동근2015

    … 43 patients with symptomatic LUTS [International Prostate Symptom Score (IPSS) over 8] and 49 healthy volunteers were enrolled. No subjects had diseases that could affect the autonomic nervous system, such as diabetes or hypertension. Electrocardiographic signals were obtained from subjects in the …

    ajou Repository record

  15. Evaluation of a stage II screening protocol for prostate cancer

    deRuiter, Wayne K.Brock University2003

    In 2003, prostate cancer (PCa) is estimated to be the most commonly diagnosed cancer and third leading cause of cancer death in Canada. During PCa population screening, approximately 25% of patients with a normal digital rectal examination (DRE) and intermediate serum prostate specific antigen …

    brock Repository record

  16. Evaluating the role of a 99mTc-HYNIC-PSMA SPECT scan following a negative bone scan in men with prostate cancer: a single-centre, retrospective cohort study

    Oppel, CleveDivision of General Surgery2023

    … high-risk and unfavourable intermediate-risk prostate cancer, who had a 99mTc-HYNIC-PSMA SPECT (technetium-99m hydrazine nicotinamide prostate-specific membrane antigen singlephoton emission computerised tomography) scan following a negative 99mTc-MDP (technetium-99m methylene diphosphonate) …

    cape-town Repository record

  17. Fabricating protein arrays using Dip-pen Nanolithography techniques for improved sensitivity of biomarker detection

    Irvine, Eleanore JaneUniversity of Strathclyde2012

    … a platform for the detection of the biomarker, prostate-specific antigen (PSA), using optical microscopy techniques. Investigations into creating a faster patterning method, with reduced feature sizes of antibodies are first detailed. The aim was to develop a diagnostic system that competes with …

    strathclyde Repository record

  18. Analysis of N-Linked Oligosaccharides of Prostate-Specific Antigen and Prostatic Acid Phosphatase in Prostatic Fluids

    White, Krista Yaudes2019

    <p>Presently, prostate cancer is the most common cancer afflicting men in the United States, with serum PSA being the "gold standard" protein biomarker used in the clinic for detecting and diagnosing prostate cancer. Nonetheless, serum PSA levels can also be elevated in non-cancerous conditions as …

    odu Repository record

  19. 병원직원의 저선량 방사선 피폭과 혈액검사 결과의 연관성

    김, 진태2016

    … 표지자 검사인 α-feto protein(AFP), Carcino-Embrionic Antigen(CEA), Prostate-Specific Antigen(PSA), Cancer Antigen(CA-125), 그리고, 갑상선 호르몬 검사인 Thyroil Stimulating Hormone(TSH), Free T4(FT4) 검사 결과를 사용하였다. 분석에 사용된 통계분석 방법은 t-test, ANOVA, 다중회귀분석을 실시하였고, 다음과 같은 결론을 얻었다. 방사선 관계 종사자의 평균 피폭선량은 남자가 …

    ajou Repository record

  20. The Effects of Physician Organization on the Disadoption of Low-Value Services: Evidence From PSA Testing and Mammography

    Sen, Aditi Priyadarshini2015

    … of low-value services in two settings: prostate cancer screening using the prostate-specific antigen (PSA) test following the 2012 guideline recommending against screening, and mammography for women under 50 following a change in the routine screening recommendation in 2009. Using claims …

    penn Repository record

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