Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 23 for “"Prostate carcinoma"”.
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Leukemia/Lymphoma Related Factor in Human Prostate Carcinoma
Benign prostatic hyperplasia (BPH) and prostate cancer (PC) are critical health problems in elderly population with PC being the most common non-dermatologic malignancy in men. Although epidermal growth factor (EGF) plays a major role in the growth of normal prostate and in the initiation and …
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MALDI Mass Spectrometry Imaging for the Discovery of Prostate Carcinoma Biomarkers
<p>The elucidation of new biological markers of prostate cancer (PCa) should aid in the detection, and prognosis of this disease. Diagnostic decision making by pathologists in prostate cancer is highly dependent on tissue morphology. The ability to localize disease-specific molecular changes in …
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The effect of temperature on the bystander effect as examined in human prostate carcinoma cells with alpha particle irradiation
… that the soluble factor released by DU-145 human prostate carcinoma cells was a short-lived, free radical species (Wang and Coderre, Rad. Res., 164, 711-722, 2005). This thesis examined the effect of temperature on the bystander effect. A co-culture system was used to create irradiated and …
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Characterization of p-type silicon semiconductor detectors for use in in vivo dosimetry
… on patients undergoing treatment for lung or prostate carcinoma. Differences in measured and calculated exit doses could be improved by the inclusion of tissue heterogeneity correction factors in the treatment planning algorithm.
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Investigating couplet strategies incorporating 4 pillars of cancer therapy
… disease stratification in dogs with urothelial carcinomas. In male dogs specifically, uroepithelial cancers include invasive urothelial carcinoma and prostate carcinoma. The inability to distinguish invasive urothelial carcinoma involving the prostate from prostate carcinoma results in …
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Chemical and molecular analysis of Libyan desert plants used in camel feed
… A375 (malignant melanoma), PANC-1 (pancreatic carcinoma), A2780 (ovarian carcinoma), ZR-75-1 (breast carcinoma), LNCaP (prostate carcinoma), and HeLa (cervical cancer) and a non-cancer (PNT2) cell line using an AlamarBlue® assay. In parallel, this study also attempted to examine miRNAs present …
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Matriptase/pdgf D/beta-Pdgfr Signaling Axis In Human Prostate Cancer: The Role Of Pten In The Regulation Of Pdgf D Expression
… shown that ?-PDGFR is upregulated in primary prostate cancer and bone metastases. However, PDGF B, formerly thought to be the sole ligand for ?-PDGFR, is not expressed in clinical prostate cancer samples. In a study of human primary prostate carcinoma and bone metastases, we found that PDGF D …
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The role of PAK6 in HGF-induced prostate cancer cell migration
Cell migration plays a significant role in carcinoma metastasis in which cancer cells move from the primary site and establish tumours at a secondary location. During tumour progression cancer cells can assume a migratory phenotype which is characterised by cell-cell dissociation and single cells …
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Combinatorial Modulation of Multiple Signaling Pathways to Gain Therapeutic Response in Breast and Prostate Cell Carcinomas
… with and without radiation to enhance breast & prostate tumor cell death both in vitro and in vivo. Previous studies from our group have shown that UCN-01 and MEK1/2 inhibitors interact to cause tumor cell death in transformed cell lines in vitro. We extended this observation to an in vivo …
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Analysis of N-Linked Oligosaccharides of Prostate-Specific Antigen and Prostatic Acid Phosphatase in Prostatic Fluids
<p>Presently, prostate cancer is the most common cancer afflicting men in the United States, with serum PSA being the "gold standard" protein biomarker used in the clinic for detecting and diagnosing prostate cancer. Nonetheless, serum PSA levels can also be elevated in non-cancerous conditions as …
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LET dependence of radiation-induced bystander effects using human prostate tumor cells
… effects in co-cultured cells. Human DU-145 prostate carcinoma cells were grown on a 1.4 [mu]m-thick mylar membrane in specially constructed cell culture dishes for irradiation with alpha particles (average energy 3.14 MeV) from a 241Am source, or in 6-well plates for irradiation with 250 kVp …
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Synthetic Peptide Ligand Mimetics and Tumor Cell Motility
… analyzed for their ability to adhere to human prostate tumor cells, support tumor cell adhesion and inhibit tumor cell adhesion to ECM proteins. Two peptides, RZ-3 (kmviywkag) and HYD1 (kikmviswkg) bound to tumor cell surfaces. A scrambled peptide derivative of HYD1, HYDS (wiksmkivkg) is not …
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“Differential regulation of PTHrP gene expression by 1,25(OH)2D3 in prostate cancer cell lines”
… hormone-related protein (PTHrP) is expressed by prostate cancer cells. Since PTHrP enhances the growth and osteolytic potential of prostate cancer cells, it is important to control PTHrP expression in these cells. 1,25-Dihydroxyvitamin D3 (1,25(OH)2D3) downregulates PTHrP expression in a variety …
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Complications to peptic ulcer and peptic ulcer surgery
… gastrectomy increases the risk of gastric carcinoma more than 20 years after surgery and enterogastric reflux is regarded as the main ethiological factor. Partial gastrectomy also gives increased risk of other malignancies as well as smoking related disease. Parietal cell vagotomy (PCV) is …
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Investigation of the role of Col4a1 and Itga11 in enzalutamide resistance of prostate cancer cells
Prostate carcinoma is the most commonly diagnosed non-cutaneous cancer in males in the Western World. Androgen Deprivation Therapy (ADT) is initially effective in patients with localized prostate cancer (PCa), but eventually, cancer cells develop resistance to therapy and progress into …
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Pharmacological studies of bioactive compounds from medicinal mushrooms in Northeast of Thailand
… F. cajanderi showed cytotoxicity against ovarian carcinoma (A2780), prostate carcinoma (LNCap) and breast carcinoma (ZR75-1)with IC50 of 149.70 µg/ml, 125.60 µg/ml and more than 150 µg/ml, respectively. While EtOH crude extracts of P. everhartii and P. laevigatus showed cytotoxicity against LNCap …
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Development of Multifunctional Nanoparticles for Cancer Therapy Applications
… showed much higher cytotoxicity to PC-3MM2 human prostate carcinoma cells compared to CNTs without paclitaxel. Paclitaxel was loaded at 112.5 µg/mg of PLGA-coated CNTs. </p><p> Iron oxide nanocomposites were functionalized with quantum dots for diagnosis applications. Because the nanocomposites …
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JNK regulates Fas receptor mediated apoptosis in prostate cancer cell lines
Prostate Cancer is a disease that primarily affects elderly men. The incidence of prostate cancer has been progressively increasing in the western world over the last two decades. Life expectancy and diet are believed to be the main factors contributing to this increase in prevalence. Prostate …
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Roles of Nanog, a transcription factor for self-renewal of embryonic stem cells, in prostate tumor initiation and chemoresistance
Prostate cancer is one of the most common cancers affecting one of every six men in United States. It is increasingly appreciated that tumor or cancer stem cells are the cells responsible for initiating tumor formation and therefore should be targeted for eradication in cancer treatment. But the …
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Register studies of cancer in the Southern Health Care Region in Sweden
… in Sweden diagnosed with colon, rectal, breast, prostate and lung cancer during the period 2000 to 2005 were identified via the Swedish Cancer Register. Lately, including the period 2006 to 2007, all persons diagnosed with cancer were analysed with specification of 18 types of cancer. The …
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