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Showing 1 to 1 of 1 for “"Prostate Cancer, Posttranscriptional Gene Silencing"”.
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Posttranscriptional gene silencing of p27 in primary prostate epithelial cells by small inhibitory RNA (siRNA)
… regulate the cell cycle have been implicated in cancer development. An important example is the common downregulation of the Cdk inhibitor p27 in prostate cancers. p27/Kip1 regulates the cell cycle by inhibiting the checkpoint kinase Cdk2/cyclin E kinase and blocking cell cycle progression in G1. …