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Showing 1 to 14 of 14 for “"Proopiomelanocortin"”.
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Manipulation and characterization of proopiomelanocortin (POMC) neurons in the hypothalamic regulation of energy balance
It is well documented that hypothalamic proopiomelanocortin (POMC) neurons are a critical component in the maintenance of energy balance. POMC neurons release peptide transmitters that modulate pathways involved in food intake, energy expenditure, and reward pathways. POMC peptide release can …
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Proopiomelanocortin gene expression in Xenopus laevis melanotrope cells: differential regulation by neuronal factors and role of second messengers
Contains fulltext : 146647.pdf (Publisher’s version ) (Open Access)
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Appetite Regulatory Neural Circuitry in the Prenatal Testosterone Treated and Obese Ewe
… protein (AgRP) and neuropeptide Y (NPY), or proopiomelanocortin (POMC) and cocaine- and amphetamine- regulated transcript (CART). We then asked whether this circuitry is altered in ewes at increased risk of obesity following prenatal testosterone (T) treatment, or in diet-induced obese ewes. …
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Endocannabinoid and lipid metabolism genes network analysis in adipose and liver tissue of dairy cows during the transition period
… (FAAH, NAAA, MGLL), and the hormone precursor proopiomelanocortin (POMC). We also examined mRNA expression via qPCR of genes associated with lipolysis (LIPE, ABDH5, ATGL), fatty acid oxidation (CPT1A, CPT2, ACADVL, ACOX1), oxidative stress (SOD1, SOD2), and genes that are involved in …
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The genetic basis of plumage polymorphism in the black sparrowhawk
… (MC1R), agouti signalling protein (ASIP), or proopiomelanocortin (POMC). However, the expression levels of several genes involved in melanogenesis differed between the two morphs, with light morph developing breast feathers showing significantly higher levels of expression of ASIP and lower …
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Life Without GPR7, the Neuropeptide W1 Receptor: Regulation of Energy Homeostasis by GPR7 and its Endogenous Neuropeptide Ligands
… hypothalamic RNA levels of neuropeptide Y and proopiomelanocortin in male GPR7-/- mice were more indicative of a lean state than a leptin deficient "starved" state. Furthermore, ob/ob GPR7-/- and Ay/a GPR7-/- double mutant male mice were heavier than normal ob/ob or Ay/a male mice suggesting …
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Lesioning of the Nucleus of the Hippocampal Commissure Followed by Food Deprivation Stress in Birds Demonstrates Simultaneous Involvement in both the Hypothalamo-Pituitary-Adrenal Axis and the Hypothalamo-Pituitary-Thyroid Axis
… the NHpC of the LES + FD group. Supporting this, Proopiomelanocortin heteronuclear RNA (POMC hnRNA) within the APit was significantly downregulated. Interestingly, PVN CRH levels were found to be significantly decreased in the LES+FD group of birds with no lesioning of the PVN itself. Results …
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Effect of age and pregnancy on the murine melanocortin system in the female reproductive system
… and signalling. The MCs are activated by proopiomelanocortin (POMC) derivatives: alpha-, beta-, and gamma-melanocyte stimulating hormones and adrenocorticotrophic hormone; while agouti signalling peptide (ASP) and agouti-related protein (AgRP) antagonise the peptide activity. The MCs were …
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Estrogen Regulation of the Pregnant Baboon Placental 11β-Hydroxysteroid Dehydrogenase (11β-HSD)-Catalyzed Metabolism of Cortisol and Cortisone and Its Effect on the Development of the Fetal Hypothalamic-Pituitary-Adrenal Axis
… expression of the mRNA for the ACTH precursor proopiomelanocortin (POMC). Pituitary POMC mRNA, was greater in baboon fetuses at term than at mid-gestation and increased on day 100 in estrogen-treated animals. Immunohistochemical studies confirmed that ACTH protein paralleled changes in POMC …
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Amino acid transmitters and the neural control of feeding and energy homeostasis
… Y / Agouti-related peptide (NPY/AgRP) and proopiomelanocortin (POMC) cells (the so-called first order feeding neurons), have been extensively studied for their roles in energy homeostasis—mostly through research into the peptides they are named after. There is clear evidence that peptides …
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Transition cows: hepatic endocannabinoid system gene expression in response to prepartal plane of nutrition and the effects of genetic merit on genes of lipid metabolism in adipose tissue
… (FAAH, NAAA, MGLL), and the hormone precursor proopiomelanocortin (POMC) in liver at -14, 7, 14, and 30 d around parturition from cows fed a control (CON; NEL = 1.34 Mcal/kg) or moderate-energy (OVER; NEL = 1.62 Mcal/kg) diet during the dry period. Expression of CNR2 and POMC was greater at 7 d …
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Mechanisms of hypothalamic regulation of food intake in birds
… sub-type 1 (NPYR1) in chicks while it increased proopiomelanocortin (POMC), MC4R, CRF, and CRFR2 in quail. These results suggested that the anorexigenic effect of CRF may involve a dampened neuropeptide Y (NPY) system in chicks whereas it is associated with activated CRF and melanocortin systems …
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Growing Up POMC: Pro-opiomelanocortin in the Developing Brain
Neurons in the arcuate nucleus of the hypothalamus (ARH) play a central role in the regulation of body weight and energy homeostasis. ARH neurons directly sense nutrient and hormonal signals of energy availability from the periphery and relay this information to secondary nuclei targets, where …
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The Multifunctional Melanocortin System in the Human Choroid
The choroid is a vascular pigmented tissue in the eye located between the outer collagenous sclera and inner neural retina. The choroid stroma includes extracellular matrix, blood vessels, immune cells, nerves, fibroblasts, and melanocytes. As one of the most abundant cells within the choroid, …