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Showing 1 to 3 of 3 for “"Promoter Directionality"”.

  1. Promoter directionality is controlled by U1 snRNP and polyadenylation signals in mouse embryonic stem cells

    … upstream and antisense from active gene promoters in mammals and yeast. Although RNAPII initiates divergently from these promoters, efficient RNAPII elongation leading to the production of a full-length, stable, abundant RNA molecule is confined to the coding sense direction. These data …

    mit Repository record for Promoter directionality is controlled by U1 snRNP and polyadenylation signals in mouse embryonic stem cells (opens in a new tab)

  2. The mechanism and function of pervasive noncoding transcription in the mammalian genome

    … that occurs at the majority of mammalian gene promoters. RNA polymerases transcribe divergently on opposite strands, producing precursor mRNAs (pre-mRNAs) on one side and promoter upstream antisense RNAs (uaRNAs) on the other side. Like typical products of pervasive transcription, uaRNAs are …

    mit Repository record for The mechanism and function of pervasive noncoding transcription in the mammalian genome (opens in a new tab)

  3. An Investigation Into The Role Of Cfia 3' End Processing Complex In The Termination And Initiation/reinitiation Of Transcription

    … strongly suggest that Clp1 participates in promoter-associated transcription. We provide multiple lines of evidence in support of a role for Clp1 at the 5′ end of genes. First, the presence of Clp1 in the vicinity of the promoter region implies its involvement early in the transcription …

    wayne-thes Repository record for An Investigation Into The Role Of Cfia 3' End Processing Complex In The Termination And Initiation/reinitiation Of Transcription (opens in a new tab)