Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 5066 for “"Proliferation"”.
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Hegemony and nuclear proliferation
… the decline is largely attributable to US nonproliferation policies, in particular the threat of sanctions that was instituted in the late 1970s. By credibly threatening to cut off economic and military support to countries pursuing nuclear weapons, I argue that this threat of sanctions deters …
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Missile Proliferation in the 1990s
The proliferation of missiles is posing new problems to policy makers in the United States and elsewhere in the industrialized world. Over the next several years the number of Third World countries possessing these weapons will continue to grow, and, significantly, the sophistication of existing …
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Biochemical investigations on cellular proliferation
The investigations described here were begun at the suggestion of Professor G. F. Marrian and. Professor J. R. Learmonth to examine the relationship between ribonucleic acids (and their derivatives) and the processes of tissue growth (including wound healing).
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Invasion and Proliferation in Malignant Cells
… of tumor cells are to acquire uncontrolled proliferation and invasive properties. This allows the tumor to grow and invade beyond the tissue from which the tumor cells originate. We here specifically studied p16 and ERK1/2 with special focus on and the relation to proliferation and invasion …
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Stochasticity and order: studies of keratinocyte proliferation
… single cell resolution. This shows two modes of proliferation: Type 1 cell division is stochastic with equal odds of generating dividing or non-dividing progeny, while Type 2 cell division predominantly produces two dividing daughters. These two modes are sufficient to explain the entire range of …
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Bioenergetics and metabolism of eukaryotic cell proliferation
Cellular growth and proliferation necessitates the transformation of cell-external nutrients into biomass. Strategies of biomass accumulation across the kingdoms of life are diverse and range from carbon fixation by autotrophic organisms to direct biomass incorporation of consumed nutrients by …
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A unified risk-Informed framework to assess the proliferation risk and license the proliferation performance of nuclear energy systems
In order to strengthen the current non-proliferation regime it is necessary to guarantee high standards of security for the sites that use, store, produce, or reprocess special nuclear materials (SNM). The current surge of interest in nuclear energy requires resolution of concerns about the …
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Investigation of Proliferation Suppressors In Genetic Fitness Screens
… there has been sparse investigation of proliferation suppressor genes, gene knockouts resulting in increased cellular growth rates, in the vast collection of genome-wide genetic screens coming from the Sanger and Broad Institute’s DepMap database. In this dissertation, we conducted a …
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ZIPRO1: Fine Tuning Proliferation in Discrete Cell Populations
… we have shown that Zipro1 is involved in proliferation GCs, Hair follicles and the Cranio-facial process. Overexpression of Zipro1 results an increase in the number of GCs, this increase in GCs directly regulates the appearance of secondary fissure in the cerebellum. Overexpression also …
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The Korean Peninsula: Perspectives on War and Proliferation
… war, and North Korea remains a source of the proliferation of weapons of mass destruction and missiles. Currently South Korea continues its transformation to a free-market, democratic and open society; whereas, North Korea retrogresses with its economically stagnant, despotic, and …
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Active Inhibition of T Cell Proliferation by Monocytes
<p>Monoclonal antibodies (mAb) to MHC class II molecules (anti-class II mAb) have been well described in their ability to inhibit T cell activation. The most current model is that anti-class II mAb interfere directly with the T cell receptor-major histocompatibility complex crosslinking which is …
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Stress Proliferation and Disability over the Life Course
… resources.</p><p>Chapter 3 examines stress proliferation among married couples. While decades of research show the health benefits of marriage, stress proliferation suggests that chronic stressors such as disability may undermine social relations, thus limiting their role as a coping …
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Regulation of Breast Cancer Cell Proliferation by APRIL
… cause of death from cancer among women. “A proliferation-inducing ligand” (APRIL) is seen in the stroma of approximately 38% of breast cancer patients. APRIL is a tumor necrosis factor superfamily member that is implicated in lymphoid cell survival, proliferation and apoptosis. APRIL studies …
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Proliferation signals: information, uncertainty, threat perception and response
… of or charged with identifying occurrences of proliferation, I argue that states must make their own determinations as to 1) whether proliferation is occurring or has occurred and 2) whether and to what extent it constitutes a threat. To do this, they rely on the interpretation of information, …
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Ssessment methodology for proliferation resistant fast breeder reactor
Due to perceived proliferation risks, current US fast reactor designs have avoided the use of uranium blankets. While reducing the amount of plutonium produced, this omission also restrains the reactor design space and has several disadvantages over blanketed cores. This study investigated many …
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Metabolic regulation of mammalian cell growth and proliferation
Proliferation requires that cells acquire sufficient biomass to produce two daughter cells. To accomplish this, cells must utilize available nutrients to generate new components of cell mass, including proteins, lipids, and nucleic acids. In addition, cells must coordinate biosynthesis and …
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The role of respiration in supporting cell proliferation
… how the various network components support proliferation may lead to improvements in cancer therapy. It has long been known that mitochondrial respiration is essential for proliferation. However, the precise metabolic role that is filled by respiration is not well defined. This thesis …
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A de-proliferation methodology for the automotive industry
Thesis (M.S.)--Massachusetts Institute of Technology, Sloan School of Management, 1994, and Thesis (M.S.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 1994.
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