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Showing 1 to 3 of 3 for “"Programmable Nuclease"”.
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Protein factors involved in the biogenesis of the mitochondrial ribosome
… We generated knockout cells lines using programmable nuclease technology, and characterised the possible effects of MRM1 depletion on mitochondrial translation and mitoribosome biogenesis. We demonstrated that neither the enzyme nor the modification is required for human mitoribosomal …
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Engineering programmable nucleases for in vivo and in vitro applications
Programmable nucleases are powerful molecular tools that have significantly advanced biotechnology development. Enzymes such as zinc-finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs), clustered regularly interspaced short palindromic repeats (CRISPR) associated …
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Computational tools for engineering functionally improved genetic components and cellular factories
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2026-08-01