Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 52 for “"Prognostic information"”.
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Towards more prognostic information to patients with life threatening diseases: Why, how and when?
… aim of this dissertation is to analyse information disclosed to patients with severe cancer prognoses, from a Swedish perspective, through two sets of interviews with patients and doctors. The aim of the first study (I) is to explore how the interviewed patients related to the …
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Investigation of Quatitative Image Features From Pretreatment Ct and Fdg-Pet Scans In Stage Iii Nsclc Patients Undergoing Defintive Radiation Therapy
… positron emission tomography (PET) could provide prognostic information to improve outcome models. Our goal for this work was to determine if it may one day be feasible to incorporate QIFs into personalized cancer care. QIFs were used to quantitatively characterize patient disease as seen on …
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Risk stratification of ICU patients using arterial blood pressure waveforms
… Variability, and Heart Rate Variability extract prognostic information from the electrocardiograph. However, there is still a wealth of data collected from ICU patients and left unused every year that can augment risk-stratification methods. This thesis extends non-invasive risk stratification to …
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Innovations in non-intrusive load monitoring
… is developed that provides diagnostic and prognostic information about equipment in real time to maintainers of electromechanical systems.
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Evaluation of serum prolidase activity as a marker for liver fibrosis in suspected liver disease
… as it imparts important clinical staging and prognostic information, is a risk marker of adverse clinical outcome yet, even if advanced, is capable of reversal. Histological examination of liver biopsy material is the reference standard in the assessment of liver fibrosis, but it is …
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Imaging Biomarkers of Response to Immune Checkpoint Inhibition in Melanoma
… could therefore provide important diagnostic and prognostic information. This project builds on existing technologies in Cambridge to develop structural and functional imaging approaches for monitoring tumour response to immune checkpoint inhibitors. Magnetic resonance imaging (MRI), …
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Multifokale Elektroretinographie bei retinalen Gefäßverschlüssen
… studies have to show if this technique can give prognostic information about neovascularisation risks. The intraindividual comparison of affected and fellow eye promises to be more sensitive than comparison with a normal collective.
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Statistical modelling for the prognostic classification of patients with pancreatic cancer for optimisation of treatment allocation
… death and is difficult to diagnose and treat. A prognostic index can be used in clinical practice to predict survival. Thirty six prognostic factor studies were identified but size and statistical methods were inappropriate. Continuous variables are often simplified incorrectly i) assuming linear …
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Identifying patients at high risk of death with novel computational biomarkers
… simultaneously providing potentially useful prognostic information on the relationship between patient outcomes and clinical variables. Moreover, artificial neural networks can provide a convenient formalism for combining rich time series information from physiological signals with more …
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Development of rate related exercise-induced myocardial ischemia and risk of selected coronary disease endpoints
… exercise test (GXT) responses, known to have prognostic importance, in the coronary artery disease population generally, can differentiate certain cardiovascular morbidity and mortality endpoints among physically active patients. Data were obtained in 1989 at three community-based cardiac …
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The significance of aberrant phenotypes and multidrug resistance for evaluation of the dynamics of minimal residual disease in acute leukemia patients /
… by flow cytometry can provide important prognostic information and help to identify groups of patients who would benefit from individualized treatment.
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Μελέτη της κλινικής σημασίας της αγγειογένεσης σε ασθενείς με νόσο hodgkin
… that angiogenesis in HL provides independent prognostic information, requiring the concomitant evaluation of quantitative and qualitative aspects of microvascular netword.
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Clinical Impact of A Highly Sensitive Next-Generation Sequencing Measurable Residual Disease Assay In Patients With Acute Lymphoblastic Leukemia
<p>Measurable residual disease (MRD) is highly prognostic for relapse and overall survival (OS) in acute lymphoblastic leukemia (ALL), although many patients with apparent “MRD negativity” by standard assays still relapse. We evaluated the clinical impact of a highly sensitive next-generation …
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MOLECULAR PROFILING OF UROTHELIAL CARCINOMA
… with muscle-invasive tumors provided independent prognostic information for lymph-node status and overall survival. In the third study (Article III), the genetic relation between syn- or metachronous tumors was explored, revealing that the expression profile is remarkably stable in tumors …
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Chracterisation of Chromosomal Aberrations in Acute Lymphoblastic Leukaemia Patients Attending the University Teaching Hospital in Lusaka
… that the genetic analysis of leukaemia has prognostic and therapeutic implications. Cytogenetic and molecular studies provide important prognostic information and are becoming important in determining the appropriate treatment protocol. The aim of this study was to characterise chromosomal …
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The design of an effective sensor fusion model for condition monitoring systems of turning processes
… to detect tool wear and provide diagnostic and prognostic information. A novel approach, termed ASPST, (Automated Sensor and Signal Processing Selection System for Turning) is used to select the most appropriate sensors and signal processing methods. The aim is to reduce the number of sensors …
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Prognostic factors in soft tissue sarcoma. Tissue microarray for immunostaining, the importance of whole-tumor sections and time-dependence.
… of the extremities and trunk wall, improved prognostic factors are needed to identify patients at high-risk for metastasis. Various factors are included in the many prognostic systems currently in use and the prognostic value of immunohistochemical (IHC) expression of biological markers is …
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Pathological, Immunohistochemical and Molecular Analysis of Recurrent Glioblastoma
… glioblastoma is controversial. To evaluate the prognostic value of the volume of residual viable tumor versus therapy-induced necrosis in the resection material and the diagnostic value of ancillary tests in recurrent glioblastoma, we conducted a retrospective review of 20 patients whose initial …
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A study of succinate dehydrogenase deficient tumourigenesis: From functional assessment of variant pathogenicity to the discovery of new disease biomarkers
… have provided additional prognostic information and prediction of malignant risk but further biomarkers are needed. Furthermore there is a lack of effective treatments for malignant disease associated with SDHx variants (8) (9). This ‘multi-omics’ investigation has provided …
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