Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 922 for “"Prognostic"”.
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Molecular prognostic factors in bladder cancer
Contains fulltext : mmubn000001_221553789.pdf (Publisher’s version ) (Open Access)
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Modelling prognostic trajectories in Alzheimer’s disease
… binary outcomes to deriving individualised prognostic scores of cognitive decline due to AD, we used a novel trajectory modelling approach (Generalised Metric Learning Vector Quantization – Scalar projection) that mines multimodal data from large AD research cohorts. Using this approach, we …
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Comprehensive Analysis of Lung Cancer Prognostic Factors
… and highly variable in prognosis. Analysis of prognostic factor is anticipated to guide clinicians for treatment selection, enhance patient care, and help understanding biological mechanism of tumor progression. To extend current knowledge about lung cancer prognosis, this dissertation analyzed …
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Prognostic modelling for residual useful life prediction
… this thesis studies new approaches for prognostic modelling of residualuseful life prediction using condition monitoring information.First, stochastic filtering models are applied for residual useful life prediction, andboth failure and censored data are utilized for model …
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Review of prognostic factors for esophageal voice
<p>Plan A of this study was completed. Plan B of the study is the subject for future research. A review of the laryngectomy literature, from the earliest mention of the laryngectomy surgical procedure to the present was conducted; with specific emphasis upon factors pertinent to laryngectomee …
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Study of prognostic markers in advanced cancer
BACKGROUND: Prognostication is a core skill fundamental to the clinical management of patients with advanced cancer. This skill is exercised to guide appropriate clinical decisions, plan supportive services and allocate resource utilisation. Prognostication by clinicians is often erroneous, …
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Telomerase a prognostic marker an therapeutic target
Malignant glioma is the most common and aggressive form of tumours and is usually refractory to therapy. Telomerase and its altered activity, distinguishing cancer cells, is an attractive molecular target in glioma therapeutics. The aim of this thesis was to silence telomerase at the genetic level …
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Novel Immunometabolic Therapies and Prognostic Markers for Lymphedema
… to target lymphedema fibrosis, and improved prognostic models are required to reliably predict who will develop chronic, severe lymphedema to appropriately triage and monitor patients for timely diagnosis and treatment. It is unknown if: (1) gene expression changes in tissue are associated …
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Diagnostic and Prognostic Biomarkers for Early Prostate Cancer
… is an urgent need for robust diagnostic and prognostic biomarkers that can accurately identify patients with prostate cancer and stratify them according to the risk of developing aggressive disease state. We addressed this issue by focusing on DNA methylation, and PTEN and ERG protein markers …
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Evaluation of novel prognostic factors In ovarian carcinoma
… and multivariate analysis. Several clinical prognostic factors were identified by univariate analysis. Additionally, using Cox's regression model the independent markers of survival and RFS were FIGO stage, and residual disease in 173 and 178 patients respectively. Data on CA 125 serum level, …
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The post-thrombotic syndrome. Etiologic and prognostic factors
Contains fulltext : 91225.pdf (Publisher’s version ) (Open Access)
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Pancreatic Cancer - Early Detection, Prognostic Factors, and Treatment
… with special reference to early detection, prognostic factors, and treatment. Methods: In paper I, 27 prospectively collected serum samples from resectable pancreatic cancer (n=9), benign pancreatic disease (n=9), and healthy controls (n=9) were analyzed by high definition mass spectrometry …
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Cardiac arrest – prognostic biomarkers and aspects of shock
… biomarkers may be a promising concept to improve prognostication. A targeted temperature of 33°C was associated with increased vasopressor requirements and increased lactate levels in both our investigated cohorts. A low MAP during the intervention (0-36 hours) was associated with poor outcome …
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Prognostic biomarkers for head and neck squamous carcinoma
Head and neck cancer is the 6th most common cancer and is generally treated with surgery and post surgical radiotherapy (RT) alone or in combination with chemotherapy (CT). Over 50% of the patients fail to respond to such treatment while suffering the undesirable side effects of radio-chemotherapy. …
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Juvenile pilocytic astrocytomas: A search for prognostic markers
… this pathway in an effort to establish reliable prognostic and predictive markers. Aims and objectives: Our study was aimed at reviewing the light microscopic features and also evaluating the BRAF, p16 and protein kinase ERK components of the MAPK pathway. The findings thereof were correlated …
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Ependymal tumours in childhood: outcomes and prognostic factors
OBJECTIVES: To retrospectively review the patient demographics, disease profile and treatment outcomes of paediatric patients treated for ependymoma at our institution. STUDY DESIGN AND METHODS: 51 eligible patients were treated between 1980 and 2013. The median age at presentation was 6 years. The …
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Novel Prognostic Markers and Therapeutic Targets for Glioblastoma
… grim outcome derive from the lack of applicable prognostic markers and effective therapeutic targets. By employing a loss of function RNAi screen in glioblastoma cells we found a list of 20 kinases that can be considered glioblastoma survival kinases. These survival kinases which we term as …
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