Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 512 for “"Progesterone"”.
-
Metabolism of progesterone
… clinical use Section IV. The Conversion of Progesterone to Urinary Pregnanediol by Human Subjects: Introduction: (1) Healthy Post -Menopausal Women (2) Healthy Young Men (3) Oestrogen pre-treated Post-Menopausal Women (4) Hysterectomised Post-Menopausal Women (5) Hypertensive Cases (6) …
-
Progesterone control of human endometrial cells
… in the stromal compartment and are influenced by progesterone, secreted by the Corpus Luteum (CL). This hormone is believed to be the main factor inducing such differentiation in the oestradiol-primed stroma. However, mediators with the ability to activate the protein kinase A/cAMP pathway, such …
-
Engineering and characterisation of anti-progesterone OBodies
… (D7) engineered to bind to the small molecule progesterone (P4) with potential applications to detect P4 in cow’s milk to evaluate pregnancy. Obody-P4 binding was characterised with an optimized ELISA system. This was followed by the engineering of improved versions of this OBody using phage …
-
Milk Progesterone as a Reproductive Management Tool
Made available in DSpace on 2014-12-14T15:29:40Z (GMT). No. of bitstreams: 1 7709142.pdf: 6498789 bytes, checksum: 68871716601c83942b2f44f1075592a3 (MD5) Previous issue date: 1976
-
Progesterone - Estrogen Interactions in the Rat Uterus
Made available in DSpace on 2014-12-14T13:39:39Z (GMT). No. of bitstreams: 1 7714928.pdf: 4658301 bytes, checksum: 6379c7b43bb1f091a21384ccb001dcb4 (MD5) Previous issue date: 1977
-
Progesterone Regulation of the GnRH Pulse Generator
… woman, following the mid-cycle ovulation, progesterone (P4) levels dramatically increase and exert a negative feedback action upon pulsatile LH secretion necessary for maintaining normal fertility. In mice, the ARN kisspeptin neurons display synchronised patterns of firing approximately …
-
Comparison of pregnancy rates, progesterone concentrations, and expression of genes associated with progesterone synthesis in heifers and mature cows
… decline in mature cows could be impaired progesterone production. Therefore relationships of parity with reproductive performance, its effect on progesterone concentrations and genes associated with progesterone synthesis were examined in this thesis. In the first experiment, breeding …
-
The Involvement of Progesterone in Glial Cell Viability
… cells will increase with the presence of the progesterone, ethynodiol diacetate, and that cell viability will increase with increasing concentration of ethynodiol diacetate. Glial cells of 1x10° cells/well were introduced into a 96-well plate and allowed to grow for 24 hours in an incubator at …
-
Factors controlling the expression of central progesterone receptors
Progesterone, a steroid hormone is closely associated with a variety of behavioural and neuroendocrine functions. Studies were undertaken to identify the control of progesterone receptor (PR) expression in avian brain tissue. In the first study, glial cells taken from newly hatched ring doves …
-
Suppression of Cervical Cancer by the Progesterone Receptor Signaling
… women, implicating a role of estrogen and progesterone in cervical cancer. Prior studies utilizing an HPV transgenic mouse model expressing E6 and E7 (K14E6/K14E7) have demonstrated the requirement of estrogen receptor alpha (ERα) and estradiol (E2) for cervical carcinogenesis. Accumulating …
-
The role of progesterone receptor in hypothalamic kisspeptin neurons
… expression. However, the roles that the progesterone receptor (Pgr) and the androgen receptor have in progesteronic and androgenic regulation of kisspeptin-mediated GnRH release have not been investigated. Previous studies indicated that Pgr has a critical role in the induction of the …
-
Small molecule inhibitors: novel probes of progesterone receptor action
The progesterone receptor (PR) is an important member of the nuclear receptor superfamily of transcription regulatory proteins. It plays vital roles in a diverse set of biological processes, from homeostasis to reproduction. PR’s major function involves binding of liganded receptor to DNA and …
-
Membrane mechanism of progesterone actions on the rat brain
P exerts modulatory effects in a variety of physiological functions in discrete brain areas of mammals. It is generally held that actions of stroids in the CNS are mediated via genomic mechanisms. However, there are at least three lines of evidence indicating that a nongenomic mechanism of P's …
-
Regulation of progesterone receptor expression and activity in uterine cells: Analysis of the molecular actions of estrogens and progestins on the progesterone receptor gene
… effects were reduced by cotreatment with progesterone or antiestrogen. To better define the molecular mechanisms controlling the $\rm E\sb2$-mediated effects, we cloned and characterized the $5\sp\prime$-region of the rat PR gene, including two functionally distinct promoters which were …
-
Effects of estrogen and progesterone on tolerance to thermal stress
Analysis of variance showed that female Harlan Sprague-Dawley rats treated with E in combination with P (EP) had a significantly higher rectal temperature (Tre) than untreated control animals and those treated with E or P alone. In E treated rats, Tre was significantly higher than control animals …
-
Mechanisms controlling in vitro progesterone synthesis by the ovine placenta
Maintenance of pregnancy in the ewe depends on progesterone synthesized by the ovaries during the first third of gestation and by the placenta during the last two-thirds of gestation. There have been few investigations of in vitro synthesis of progesterone by the ovine placenta or of mechanisms …
-
Progesterone and Prolactin Profiles of the Female Asian Elephant (Elephas Maximus)
Serum progesterone and prolactin concentrations were determined daily (around estrus), weekly (throughout the estrous cycle), and bimonthly (during gestation) in 8 female Asian elephants. A total of 18 estrous cycles with 4 resulting in conception are described. Early gestational values are shown …
-
The Effects of Progesterone on Extracellular Serotonin Levels in Rat Hypothalamus
Progesterone effects on extracellular serotonin were monitored in the ventromedial hypothalamus (VMN), midbrain central grey (MCG) and medical preoptic area (POA) using microdialysis. Rats primed with estradiol benzoate (5 μg) were anesthetized with choral hydrate (400 mg/kg, i.p.). Samples were …
-
Estrogen Receptor and Progesterone Receptor Synthesis and Degradation in Target Cells
… the turnover of the estrogen receptor (ER) and progesterone receptors (PR) in rat uterine and human breast cancer cells, respectively, and to examine the effect of estrogen and progestin on PR levels.
Page 1 of 26