Global ETD Search

Mechanisms and Functional Consequences of Cardiac Remodeling: Role of Myocardial Rac1 and Vascular Profilin1 Genes

Elnakish, Mohammad T.The Ohio State University2013

… (LV) hypertrophy. Previously, we have shown that profilin-1 overexpression in the blood vessel medial layer of transgenic mice favoring F-actin induces stress fiber formation and plays an important role in vascular hypertrophy by inducing internal mechanical stress, leading to vascular remodeling …

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Einfluss der Mutation T109M auf die Proteinbindungseigenschaften von Profilin1: weiterführende Untersuchung der ALS-assoziierten Mutation

Schöpflin, MarcelUniversität Ulm

ulm-diss Repository record for Einfluss der Mutation T109M auf die Proteinbindungseigenschaften von Profilin1: weiterführende Untersuchung der ALS-assoziierten Mutation (opens in a new tab)

Biochemical and Structural Insights into VCP Unfoldase and WRN Helicase Complexes

Vostal, Lauren E2027

… VCP interactors. Interestingly, we identify profilin-1 (PFN1), an actin monomer-binding protein, as a top hit in one of our proteomics datasets. We examine the interaction between VCP and PFN1 using a biochemical pulldown assay and computational modeling. In collaboration with Eric Vitriol, …

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Proteomic investigation of the molecular targets of mycophenolic acid in human cells

Qasim, Muhammad2012

… protein 12, myosin regulatory light chain 2, and profilin 1), while 5 proteins were down-regulated (protein SET, stathmin, 40S ribosomal protein S12, histone H2B type 1 A, and histone H2B type 1-C/E/F/G/I). Functional annotation tool analysis showed that MPA modulated proteins were mainly involved …

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