Global ETD Search
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Showing 1 to 4 of 4 for “"Processing-body"”.
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Functions of Deadenylation Factors In Mrna Decay and Mrna Processing Body Formation
… degraded in dynamic cytoplasmic foci termed mRNA processing bodies, or P bodies, which are conserved in eukaryotes. To shed new light on the mechanisms of P body formation and P body functions, I focused on the link between deadenylation factors and P bodies. I found that the two major …
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Investigating processing body condensation, material properties and function during early Drosophila development
… phase separation. Conserved across eukaryotes, Processing bodies (P bodies) are cytoplasmic biomolecular condensates which act as hubs for RNA regulation including storage, translation, and degradation. During Drosophila oogenesis, several maternal mRNAs are stored and translationally repressed …
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Relationship between Processing Body Formation, Epithelial-to-Mesenchymal Transition, and Invasion in Lung Adenocarcinoma
… contexts, TGFβ1 enhances the formation of processing-bodies (P-bodies) where P-body proteins are required for invasion in multiple cancerous cell lines. P-bodies are a type of ribonucleoprotein (RNP) granule that assist in post-transcriptional gene regulation by storing or degrading mRNAs. …
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Characterising FAM117 proteins as novel targets of DYRK1B
… DYRK1B function, in this case the promotion of processing body formation. From observing FAM117 localisation I also show that they partially co-localise with cytoskeletal proteins, such as tubulin, and show strong co-localisation with focal adhesion proteins. FAM117 proteins are reported to be …