Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"Process impurities"”.
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Studies in the synthesis and impurity profiling of pharmacologically active benzodifurans
… active benzodifurans are complex multi-step processes and each individual step has the potential for considerable side-product/impurity formation. This project focused on synthetic strategies to benzofuran and benzodifuran derivatives in addition to their hydrogenated and substituted …
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AI-assisted reaction impurity prediction and inverse structure elucidation
Identification and control of impurities play a critical role in chemical process development for drug substance synthesis. Most chemical reactions result in a number of by-products and side-products, along with the intended major product. While chemists can predict many of the main process …
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Scale-up and optimisation of the β-chloroacrylamide process by batch and continuous flow methods
… to optimise and scale-up a complex API-like process through advanced process control to yield the final product with optimum quality and phase purity. The first chapter of this thesis presents an overview of the mechanistic pathway leading to the formation of these compounds along with the …