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Showing 1 to 1 of 1 for “"Procaspase activation to induce cell death"”.
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The discovery and characterization of anticancer procaspase activating compounds
One key hallmark of cancer is its ability to evade apoptotic cell death. In normal cells, the apoptotic intrinsic and extrinsic pathways converge on the activation of executioner cysteine aspartate proteases caspases-3 and -7. However, cancer cells are able to escape apoptosis through mutations …