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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.

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Showing 1 to 20 of 286 for “"Pro-inflammatory cytokines"”.

  1. Metabolism in Vascular Endothelial Cells: Effects of Hyperglycaemia, Pro-Inflammatory Cytokines and Polyphenols

    Ozyel, BesimUniversity of East Anglia2013

    … the deleterious effects of hyperglycaemic or inflammatory conditions on the vascular endothelium by modulating endothelial cell metabolism. Results: First, the effects of high-glucose concentrations, inflammatory cytokines and polyphenols on markers of endothelial cell function in HUVECs were …

    east-anglia Repository record

  2. Role of Activated Macrophages and Pro-Inflammatory Cytokines in Placental Trophoblast Invasion and Fetal Outcome

    Renaud, Stephen2008

    … also been linked to an increased presence of pro-inflammatory cytokine-secreting (activated) macrophages at the fetal-maternal interface. In particular, increased production of tumour necrosis factor-alpha (TNF) by activated macrophages has been implicated as a causative factor mediating …

    queens Repository record

  3. Effects of vitamin D on pro-inflammatory cytokines associated with Non-alcoholic fatty liver disease

    Ayouk, Nypiat MartinCreighton University2016

    … liver disorder in the United States, affecting approximately one-third of the population. The prevalence of NAFLD increases to 90% in morbidly obese individuals. Many studies have shown a negative association between NAFLD and vitamin D levels. In fact, low vitamin D levels were correlated to …

    creighton Repository record

  4. Physical activity for health: the impact of exercise on the human gut microbiota and pro-inflammatory cytokines

    Cronin, OwenUniversity College Cork2018

    Introduction: Promotion of regular physical activity is a critical tool in the fight against chronic disease. However, our knowledge of the interplay between host organ systems and exercise is limited, preventing us from harnessing the full potential exercise promises in the prevention and …

    cork Repository record

  5. Use of Cholera Toxin B as a Vaccine Adjuvant Activates Antigen Presenting Cells and Stimulates Production of Pro-Inflammatory Cytokines

    Romlein, Heather C.2014

    … For Disease Control. To date, there is no approved vaccine to provide protection against this pathogen. Previous <em>in vivo </em>studies with mice<em> </em>have shown that a mucosally targeted vaccine preparation of inactivated <em>F. tularensis</em> (<em>iFt</em>) adjuvanted with Cholera …

    shu-thes Repository record

  6. Effects of pelvic 3D-CRT versus IMRT radiation therapy on circulating pro-inflammatory cytokines in high risk Prostate Cancer patients

    Douvi, GeorgiaBrock University2018

    … radiation therapy on the levels of circulating pro-inflammatory cytokines (cPIC) in high-risk prostate cancer patients, who received pelvic radiation therapy delivered either by 3-dimensional radiation therapy pelvic (3D CRT) or intensity-modulated radiation therapy (IMRT). Subjects included 90 …

    brock Repository record

  7. The Association Between Pro-Inflammatory Cytokines and C-Reactive-Protein and the Cognitive and Neurological Outcome in Stroke Survivors: A Systematic Review

    Kahnami, Leila2021

    The role of inflammation in neurological prognosis of stroke has been studied previously. However, very little research has thoroughly examined the association between inflammatory markers and neurocognitive outcome post-stroke. Our main goal was to examine the existing literature and this …

    york Repository record

  8. Brain Inflammation Regulated by PINK1

    김, 준2012

    … to 24 h after slicing, mRNA expression levels of pro-inflammatory cytokines (TNF-a, IL-1b, and IL-6) measured at 6 to 24h were higher in KO slices. Expression of inducible nitric oxide synthase (iNOS) was not detected in either KO or WT slices. Furthermore, nitrite production was continuously …

    ajou Repository record

  9. Metabolic and functional approaches to investigate the effects of cytokines on the physiology of in-vitro and in-vivo models of diabetic retinopathy

    Shivashankar, GaganashreeResearchSpace@Auckland2022

    … vessel damage and is categorized into early non-proliferative and late proliferative stages. Although DR becomes clinically evident only when vascular damage has occurred to the retina, the onset of pathology occurs much earlier than the clinical manifestation. Several studies have reported that …

    auckland-ms Repository record

  10. Aging Exacerbates the Brain Response to a Peripheral Immune Stimulus

    Richwine, Amy FrancisUniversity of Illinois at Urbana-Champaign2007

    … agents stimulate macrophages in the periphery to produce pro-inflammatory cytokines (IL-1beta, IL-6, and TNFalpha) that convey a message to the brain to stimulate microglia and elicit sickness behaviors. However, excessive or prolonged release of cytokines can cause severe behavior deficits and …

    uiuc Repository record

  11. Functional Characterization of the Avian Inflammatory Mediators Nod1, MIF and IL-22

    Kim, SungwonVirginia Tech2011

    … nucleotide-binding oligomerization domain protein 1 (Nod1) and Nod2 initiate host innate immune response by recognition of specific bacterial molecules, resulting in the production of pro-inflammatory cytokines, chemokines, and anti-microbial peptides. A candidate sequence of chicken Nod1 …

    vt Repository record

  12. Cytokine patterns in a comparative model of arenavirus infection: Implications for virulence and control of viral replication

    Erin P. ScottThe University of Texas Medical Branch2005

    Guinea pig infection with the arenavirus Pichinde provides an animal model for human Lassa fever, a disease that affects 300,000 to 500,000 people a year in western Africa. Low passage Pichinde virus (P2) induces a mild disease with low viremia, while high passage Pichinde (P18) induces a severe …

    utmb Repository record

  13. The effects of fish oil supplementation on inflammation markers in chronic kidney disease patients.

    Deike, Erika.Baylor University.2010

    … acid + 1000 mg Docosahexaenoic acid), on pro-inflammatory cytokines, IL-1β, IL-6, and TNF-α for 8 weeks in CKD patients, stages 2-5. One prevalent characteristic of all stages of CKD is excessive production of these pro-inflammatory cytokines. Fish oil supplementation has been claimed to …

    baylor Repository record

  14. Differential regulation and functions of the ZFP36-family RNA binding proteins in CD8⁺ memory T cells

    Jones Evans, MarianUniversity of Cambridge2024

    … or malignant cells via cytotoxicity and the production of pro inflammatory cytokines and chemokines. In addition to antigen-specific responses mediated by the TCR, pro-inflammatory cytokines such as IL-12 and IL-18 can induce antigen-independent bystander activation of memory T cells. The …

    cambridge Repository record

  15. Gene expression in synovial fibroblasts from rheumatoid arthritis and osteoarthritis patients Novel expression of IL-19 and IL-22 by fibroblasts

    MacDonald, Daniel FrancisUniversity of Ottawa (Canada)2013

    … was to study gene expression related to cytokines and cytokine receptors in FLS. We were looking for any previously unidentified cytokines and receptors that may play a role in the pathogenesis of RA. Using a microarray-based approach to identify any potential expressed cytokine genes we …

    ottawa-retro Repository record

  16. Characterization of cholesterol 25-hydroxylase expression in human macrophages

    Magoro, Tshifhiwa2019

    … (CH25H) has been shown to exert broad antiviral properties. Given its antiviral activities, CH25H is part of an increasingly appreciated connection between type I interferon (IFN-I) and lipid metabolism. Moreover, the details of this connection appear to differ in mouse and human cells. …

    venda Repository record

  17. The Role of Inflammation in the Pathobiology of TB/HIV Co-infection

    Huante, MatthewThe University of Texas Medical Branch at Galveston2021

    … inflammation. We observed greater pathology, inflammatory influx, and increased pro-inflammatory cytokines (e.g. IL-1, TNF) in co-infected HuMouse lung. Using primary human monocyte-derived macrophages (MDM) and an in vitro co-infection system, we further observed greater cell death and …

    utmb Repository record

  18. The Role of Inflammation in the Pathobiology of TB/HIV Co-infection

    Huante, MatthewThe University of Texas Medical Branch at Galveston2021

    … inflammation. We observed greater pathology, inflammatory influx, and increased pro-inflammatory cytokines (e.g. IL-1, TNF) in co-infected HuMouse lung. Using primary human monocyte-derived macrophages (MDM) and an in vitro co-infection system, we further observed greater cell death and …

    utmb Repository record

  19. Targeted Delivery of Surface Modified Nanoparticles: Modulation of Inflammation for Acute Lung Injury

    Desu, Hari R.2016

    … events: I) pulmonary edema, II) excessive pro-inflammatory cytokines and chemokines production from alveolar epithelial and endothelial cells and III) leukocyte migration from blood circulation into alveoli. Currently, there is no FDA approved pharmacological treatment available except the …

    tenn-hsc Repository record

  20. Epidermicin NI01 and human β-defensin 2 as modulators of macrophage subset responses

    Durante, Barbara2020

    … effects on macrophages, a key cell population in inflammatory responses that mediates communication between innate and adaptive immunity. Macrophages are a pleiotropic cell population composed of different subsets that orchestrate diverse stages of inflammation with roles ranging from pro- to …

    plymouth Repository record

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