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Showing 1 to 2 of 2 for “"Prion gene (Prnp)"”.
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Landscape genetics and CWD in white-tailed deer
… spread. Chronic wasting disease is an infectious prion encephalopathy in cervids that is endemic to Colorado and Wyoming but has spread across the US within the last decade. Quantifying white-tailed deer movement and population structure in infected areas can facilitate predictions of CWD spread …
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Developmental Regulation of Prion Expression in Cattle and Mouse Embryonic Stem Cells
The host encoded cellular prion protein (PrPC) is an N-linked glycoprotein tethered to the cell membrane by a glycophosphatidylinositol (GPI) anchor. Under certain conditions, PrPC can undergo conversion into a conformationally-altered isoform (PrPSc) widely believed to be the pathogenic agent of …