Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"Primary sclerosing cholangitis"”.
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Primary sclerosing cholangitis
Thirty six consecutive patients with primary sclerosing cholangitis (PSC), 20 males median age 42 years, were studied in order to define prognostic variables and determine the influence of surgery on outcome. Presentation was usually with insidious cholestasis or recurrent cholangitis. Twenty six …
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Primary sclerosing cholangitis: from genetic risk to disease biology
Primary sclerosing cholangitis: from genetic risk to disease biology Elizabeth Claire Goode One in 10,000 people in the Western world lives with Primary Sclerosing Cholangitis (PSC), an immune-mediated, inflammatory disease of the bile ducts that is highly co-morbid with inflammatory bowel disease …
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Study of the Phenotypic Characteristics and Genetic Risk Factors of Primary Sclerosing Cholangitis
Primary sclerosing cholangitis (PSC) is a progressive chronic cholestatic liver disease, affecting young males predominantly. It causes stricturing of the intrahepatic and extrahepatic bile ducts, often leading to biliary cirrhosis, with an increased risk of colorectal and hepato-biliary …
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MAdCAM-1 expression and function in human liver
… its expression in liver diseases such as primary sclerosing cholangitis (PSC) and autoimmune hepatitis (AIH) that complicate IBD, therefore understanding the factors that drive hepatic expression of MAdCAM-1 might elucidate the pathogenesis of these diseases. In vitro stimulation of HSEC …
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Elucidating the biology of G-protein coupled receptor 35
… attention as a coding variant is linked to primary sclerosing cholangitis (PSC) and ulcerative colitis (UC). GPR35 is also upregulated in numerous cancers. Multiple studies of GPR35 have so far fallen short of revealing its core biology. In this project we set out to gain further …
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Chronic hepatitis at Groote Schuur Hospital: 1978-1996 : a literature review of the syndrome, its clinical spectrum and management at Groote Schuur Hospital
… excluded. These include Wilson's disease, Primary biliary cirrhosis, Primary sclerosing cholangitis, alpha-1-antitrypsin deficiency, alcohol abuse and iron over load states.
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Salivary proteome investigation for Autoimmune Liver Diseases classification and biomarker discovery
… liver diseases: Autoimmune Hepatitis (AIH), Primary Biliary Cholangitis (PBC), and Primary Sclerosing Cholangitis (PSC). Saliva, as a mirror of oral and systemic health, represents a promising biofluid for biomarker discovery. Several studies evidenced that various systemic disorders affected …
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Machine learning and data analytics for liver disease modeling
Primary sclerosing cholangitis (PSC) is a rare, progressive cholestatic liver disease characterized by bile duct inflammation, hepatic fibrosis, and a markedly increased risk of malignancy. Despite its severity, the underlying pathophysiology of PSC remains incompletely understood, and effective …
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Clinical, Diagnostic, Therapeutic and Prognostic Aspects of Autoimmune Liver Diseases /// Клинико-диагностични, терапевтични и прогностични аспекти на автоимунните чернодробни болести
Темата на дисертацията е свързана със сравнително редките автоимунни болести на черния дроб – автоимунен хепатит (АИХ), първичен билиарен холангит (ПБХ), първичен склерозиращ холангит и наслагващи се синдроми. За първи път у нас е извършена цялостна характеристика на автоимунните чернодробни …