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Showing 1 to 1 of 1 for “"Primaquine -- toxicity; Hemolysis -- drug effects"”.
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Covalent Binding and other Mechanisms of Primaquine Toxicity
<p>A dose-dependent covalent binding of primaquine to mouse liver microsomal protein was found in both in vitro and in vivo studies. The binding in vitro was linear during the first 90 minutes of incubation and dependent on the concentration of mouse liver microsomal protein. The in vitro covalent …