Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"Prickle1"”.
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The Role of PRICKLE1 in the Regulation of Uterine Structure and Physiology
… migration, and differentiation. Dysregulation of PRICKLE1 is implicated in various diseases, including cancer and epilepsy. In UL, PRICKLE1 is proposed to be essential for REST nuclear localization, with its dysregulation contributing to aberrant gene expression and enhanced PI3K/AKT-mTOR …
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A Novel Molecular Pathway Involving GPR10, REST, and PRICKLE1 in the Pathogenesis of Uterine Leiomyoma
… in UL, we found significant under-expression of PRICKLE1, the protein required for REST localization to the nucleus. We have found that PRICKLE1 expression in the uterine myometrium is regulated by estrogen through Estrogen Receptor-α and that the loss of PRICKLE1 leads to the destabilization and …